Gene Symbol | Pla2g2c |
---|---|
Entrez Gene | 18781 |
Alt Symbol | - |
Species | Mouse |
Gene Type | protein-coding |
Description | phospholipase A2, group IIC |
Other Description | 14 kDa phospholipase A2|GIIC sPLA2|PLA2-8|group IIC secretory phospholipase A2|phosphatidylcholine 2-acylhydrolase 2C|sPLA2-IIC |
Swissprots | P48076 |
Accessions | EDL13275 P48076 BC029347 AAH29347 CA464794 U18119 AAC52936 NM_008868 NP_032894 |
Function | PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. Testis PA2 may be important in the production of prostaglandins, by the release of arachidonic acid, which in turn are necessary for the contractions of the seminiferous tubules and the testicular capsule; they also seem to decrease sperm transit time through the male reproductive tract. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Testis specific. |
Top Pathways | Vascular smooth muscle contraction, Pancreatic secretion, Fat digestion and absorption, Ether lipid metabolism, Glycerophospholipid metabolism |
group IIC sPLA2 CRISPR/Cas9 KO Plasmid (m) - sc-422282 from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 HDR Plasmid (m) - sc-422282-HDR from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 Double Nickase Plasmid (m) - sc-422282-NIC from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 Double Nickase Plasmid (m2) - sc-422282-NIC-2 from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 CRISPR Activation Plasmid (m) - sc-422282-ACT from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 CRISPR Activation Plasmid (m2) - sc-422282-ACT-2 from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 Lentiviral Activation Particles (m) - sc-422282-LAC from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 Lentiviral Activation Particles (m2) - sc-422282-LAC-2 from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA 2 siRNA (m) - sc-145771 from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 shRNA Plasmid (m) - sc-145771-SH from Santa Cruz Biotechnology
|
||||||||
group IIC sPLA2 shRNA (m) Lentiviral Particles - sc-145771-V from Santa Cruz Biotechnology
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN38819 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND38819 from Sigma-Aldrich
|
||||||||
PLA2G2C siRNA (Mouse) - CRM3104 from Cohesion Biosciences
|
||||||||
shRNA set against Mouse Pla2g2c (NM_008868.3) - SHH376752 from Creative biogene
|
||||||||
Mouse PLA2G2C siRNA - orb282580 from Biorbyt
|
||||||||
PLA2G2C shRNA Plasmid (Mouse) - CHM3104 from Cohesion Biosciences
|