Gene Symbol | ITGAL |
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Entrez Gene | 3683 |
Alt Symbol | CD11A, LFA-1, LFA1A |
Species | Human |
Gene Type | protein-coding |
Description | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
Other Description | CD11 antigen-like family member A|LFA-1 alpha|LFA-1A|antigen CD11A (p180), lymphocyte function-associated antigen 1, alpha polypeptide|integrin alpha-L|integrin gene promoter|leukocyte adhesion glycoprotein LFA-1 alpha chain|leukocyte function-associated molecule 1 alpha chain|lymphocyte function-associated antigen 1 |
Swissprots | Q9UBC8 O43746 Q96HB1 Q45H73 P20701 |
Accessions | AAA16474 AAC31672 AAZ38713 CAA80461 EAW52243 EAW52244 EAW52245 P20701 AK298674 BAG60839 AK303190 BAG64283 AK314246 BAG36913 BC008777 AAH08777 CA430398 DC324373 Y00796 CAA68747 XM_005255313 XP_005255370 XM_006721044 XP_006721107 XM_011545849 XP_011544151 XR_950794 NM_001114380 NP_001107852 NM_002209 NP_002200 |
Function | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Leukocytes. |
Top Pathways | Malaria, Rap1 signaling pathway, Epstein-Barr virus infection, HTLV-I infection, Rheumatoid arthritis |
Human CD11a peptide - ab90246 from Abcam
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Human CD11a peptide - ab90248 from Abcam
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ITGAL / CD11a Antibody Blocking Peptide - LS-E2622 from LifeSpan Bioscience
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ITGAL / CD11a Antibody Blocking Peptide - LS-E27116 from LifeSpan Bioscience
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ITGAL-Antibody-Center-Blocking-peptide - BP13692c from Abgent, a WuXi AppTec company
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Recombinant Human Integrin alpha L beta 2, CF - 3868-AV-050 from R&D Systems
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Recombinant Mouse Integrin alpha L beta 2, CF - 7825-AB-050 from R&D Systems
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Human LFA1a Protein - abx067847 from Abbexa
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CD11a Peptide - AC21-1937-P from Abcore
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ITGAL Peptide - 42-769P from ProSci
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CD11a/Integrin alpha-L fusion protein - Ag7813 from Proteintech Group
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CD11a/Integrin alpha-L fusion protein - ag7920 from Proteintech Group
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Recombinant Lymphocyte Function Associated Antigen 1 Alpha (LFA1a) - RPB572Hu01 from Uscn Life Science Inc.
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Recombinant Lymphocyte Function Associated Antigen 1 Alpha (LFA1a) - RPB572Mu01 from Uscn Life Science Inc.
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Recombinant Lymphocyte Function Associated Antigen 1 Alpha (LFA1a) - RPB572Mu02 from Uscn Life Science Inc.
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Recombinant Lymphocyte Function Associated Antigen 1 Alpha (LFA1a) - RPB572Ra01 from Uscn Life Science Inc.
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Recombinant Lymphocyte Function Associated Antigen 1 Alpha (LFA1a) - RPB572Hu01 from Cloud-clone
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Recombinant Human Integrin alpha-L(ITGAL) ,partial - CSB-YP011875HU CSB-EP011875HU CSB-BP011875HU CSB-MP011875HU from Cusabio
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Recombinant Human Integrin alpha L beta 2 Protein, CF - 3868-AV from R&D Systems
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Recombinant Mouse Integrin alpha L beta 2 Protein, CF - 7825-AB from R&D Systems
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CD11a / ITGAL (transcript variant 1) - TP321297 from Acris Antibodies
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CD11A/integrin alpha L, Peptide - MBS426430 from MyBioSource
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ITGAL Peptide, Human - M34GP07797H from Creative Peptides
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CD11A peptide - orb13080 from Biorbyt
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ITGAL Recombinant Protein (OPCD04920) - OPCD04920 from Aviva Systems Biology
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