Gene Symbol | PSCA |
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Entrez Gene | 8000 |
Alt Symbol | PRO232 |
Species | Human |
Gene Type | protein-coding |
Description | prostate stem cell antigen |
Other Description | - |
Swissprots | O43653 Q6UW92 |
Accessions | CAL69804 CDH61610 CDH92562 EAW82312 EAW82313 O43653 AF043498 AAC39607 AI685668 AJ297436 CAB97347 AY358912 AAQ89271 BC023582 AAH23582 BC048808 BC065183 AAH65183 BI758811 BM768967 BU157227 CB993163 HQ447653 ADQ32138 NM_005672 NP_005663 NR_033343 |
Function | May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro. {ECO:0000269|PubMed:18488030}. |
Subcellular Location | Cell membrane; Lipid-anchor, GPI-anchor. |
Tissue Specificity | Highly expressed in prostate (basal, secretory and neuroendocrine epithelium cells). Also found in bladder (transitional epithelium), placenta (trophoblasts), stomach (neuroendocrine cells), colon (neuroendocrine cells) and kidney (collecting ducts). Overexpressed in prostate cancers and expression is correlated with tumor stage, grade and androgen- independence. Highly expressed in prostate cancer bone metastases. Expressed in gastric epithelial cells, mainly in the isthmus (at protein level). Not detected in normal intestinal epithelium (at protein level). {ECO:0000269|PubMed:10713670, ECO:0000269|PubMed:18488030}. |
Human PSCA protein fragment - ab159927 from Abcam
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PSCA Antibody Blocking Peptide - LS-E3063 from LifeSpan Bioscience
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PSCA Antibody Blocking Peptide - LS-E26905 from LifeSpan Bioscience
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PSCA Antibody Blocking Peptide - LS-E15547 from LifeSpan Bioscience
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Recombinant Human PSCA Protein - H00008000-Q01 from Novus Biologicals
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PSCA Peptide - P0385 from Novus Biologicals
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PSCA Peptide - NB100-91938PEP from Novus Biologicals
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PSCA-Antibody-Center-Blocking-Peptide - BP1419c from Abgent, a WuXi AppTec company
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PSCA (aa27-40) blocking peptide - GTX88530-PEP from GeneTex
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Recombinant human Prostate stem cell antigen (OPCA00944) - OPCA00944 from Aviva Systems Biology
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Human PSCA protein - orb245524 from Biorbyt
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Human PSCA protein - orb244466 from Biorbyt
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PSCA Immunizing peptide - orb17319 from Biorbyt
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PSCA Blocking Peptide - 33R-9358 from Fitzgerald
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PSCA protein - 30R-3214 from Fitzgerald
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Human PSCA Protein - abx068705 from Abbexa
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Human PSCA Protein - abx068706 from Abbexa
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PSCA Blocking Peptide - abx063455 from Abbexa
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PSCA Peptide - AC21-1737-P from Abcore
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PSCA - H00008000-Q01-10 from Acris Antibodies
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PSCA - H00008000-Q01-25 from Acris Antibodies
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Prostate Stem Cell Antigen (PSCA), Human - 20-8566 from ARP American Research Products
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Prostate Stem Cell Antigen (PSCA), Human - 20-8567 from ARP American Research Products
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PSCA Peptide - 46-968P from ProSci
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PSCA fusion protein - Ag10710 from Proteintech Group
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