Gene Symbol | PIGB |
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Entrez Gene | 9488 |
Alt Symbol | GPI-MT-III, PIG-B |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylinositol glycan anchor biosynthesis, class B |
Other Description | GPI mannosyltransferase 3|GPI mannosyltransferase III|dol-P-Man dependent GPI mannosyltransferase|phosphatidylinositol glycan, class B|phosphatidylinositol-glycan biosynthesis class B protein |
Swissprots | Q8WVN7 Q53FF9 Q92521 |
Accessions | CAH05366 EAW77480 Q92521 AK093138 AK223330 BAD97050 AK293666 BAG57112 AK314706 BAG37253 BC017711 AAH17711 D42138 BAA07709 DA598474 XM_005254795 XP_005254852 XM_011522235 XP_011520537 XM_011522236 XP_011520538 XM_011522237 XP_011520539 XR_931950 NM_004855 NP_004846 |
Function | Mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers the third alpha-1,2-mannose to Man2-GlcN-acyl-PI during GPI precursor assembly. {ECO:0000269|PubMed:8861954}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:8861954}; Multi-pass membrane protein {ECO:0000269|PubMed:8861954}. |
Top Pathways | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis |
PIG-B CRISPR/Cas9 KO Plasmid (h) - sc-411286 from Santa Cruz Biotechnology
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PIG-B HDR Plasmid (h) - sc-411286-HDR from Santa Cruz Biotechnology
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PIG-B Double Nickase Plasmid (h) - sc-411286-NIC from Santa Cruz Biotechnology
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PIG-B Double Nickase Plasmid (h2) - sc-411286-NIC-2 from Santa Cruz Biotechnology
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PIG-B CRISPR Activation Plasmid (h) - sc-411286-ACT from Santa Cruz Biotechnology
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PIG-B CRISPR Activation Plasmid (h2) - sc-411286-ACT-2 from Santa Cruz Biotechnology
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PIG-B Lentiviral Activation Particles (h) - sc-411286-LAC from Santa Cruz Biotechnology
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PIG-B Lentiviral Activation Particles (h2) - sc-411286-LAC-2 from Santa Cruz Biotechnology
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PIG-B siRNA (h) - sc-72355 from Santa Cruz Biotechnology
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PIG-B shRNA Plasmid (h) - sc-72355-SH from Santa Cruz Biotechnology
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PIG-B shRNA (h) Lentiviral Particles - sc-72355-V from Santa Cruz Biotechnology
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PIGB RNAi - H00009488-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN16783 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16783 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01450 from Sigma-Aldrich
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PIGB siRNA (Human) - CRH6300 from Cohesion Biosciences
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shRNA set against Human PIGB (NM_004855.4) - SHH375364 from Creative biogene
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shRNA set against Human PIGB(NM_004855.4) - SHR113926 from Creative biogene
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Human PIGB siRNA - orb266802 from Biorbyt
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PIGB shRNA Plasmid (Human) - CHH6300 from Cohesion Biosciences
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PIGB miRNA 3'UTR clone - MiUTR1H-07888 from Creative biogene
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