| Gene Symbol |
EIF4ENIF1
|
| Entrez Gene |
56478
|
| Alt Symbol |
4E-T, Clast4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
eukaryotic translation initiation factor 4E nuclear import factor 1
|
| Other Description |
2610509L04Rik|eIF4E transporter|eIF4E-transporter|eukaryotic translation initiation factor 4E transporter
|
| Swissprots |
B1AKL2 Q9H708 B1AKL3 Q8NCF2 B2RBF1 Q9NRA8
|
| Accessions |
EAW59977 EAW59978 EAW59979 Q9NRA8 AA609351 AF240775 AAF81693 AK025254 BAB15092 AK074768 BAC11194 AK130061 AK299136 BAG61188 AK314636 BAG37198 BC012734 AAH12734 BC032941 AAH32941 BC033028 AAH33028 CR456386 CAG30272 CU012945 CAK54376 CU013233 CAK54675 DA336484 DQ655937 DQ656044 DQ892481 ABM83407 DQ895692 ABM86618 XM_005261686 XP_005261743 XM_005261687 XP_005261744 XM_005261688 XP_005261745 XM_006724281 XP_006724344 XM_011530280 XP_011528582 XM_011530281 XP_011528583 XM_011530282 XP_011528584 XR_937877 XR_937878 XR_937879 NM_001164501 NP_001157973 NM_001164502 NP_001157974 NM_019843 NP_062817
|
| Function |
Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:22090346}. Nucleus {ECO:0000269|PubMed:22090346}. Nucleus, PML body {ECO:0000269|PubMed:22090346}. Nucleus speckle {ECO:0000269|PubMed:22090346}. Note=Predominantly cytoplasmic. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Localization to nuclear foci and speckles requires active transcription.
|
| Tissue Specificity |
Widely expressed.
|
![Western Blot: eIF4ENIF1 Overexpression Lysate (Adult Normal) [NBP2-06705] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for eIF4ENIF1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9769_eIF4ENIF1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06705-img0001.jpg)
![Western Blot: eIF4ENIF1 Overexpression Lysate (Adult Normal) [NBP2-10221] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for eIF4ENIF1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7529_eIF4ENIF1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10221-img0001.jpg)