| Gene Symbol |
EAF1
|
| Entrez Gene |
85403
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ELL associated factor 1
|
| Other Description |
ELL (eleven nineteen lysine-rich leukemia gene)-associated factor 1|ELL-associated factor 1
|
| Swissprots |
Q96JC9 B4E3F5 Q8IW10
|
| Accessions |
EAW64234 Q96JC9 AA626023 AF272973 AAK58687 AK023217 AK304697 BAG65467 AK312330 AL698790 AW292089 BC029294 BC035167 BC041329 AAH41329 BI459315 BM836669 BM918150 BQ064584 XM_005265518 XP_005265575 XM_011534165 XP_011532467 XM_011534166 XP_011532468 NM_033083 NP_149074
|
| Function |
Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. {ECO:0000269|PubMed:11418481, ECO:0000269|PubMed:16006523}.
|
| Subcellular Location |
Nucleus speckle. Nucleus, Cajal body. Note=Colocalizes with ELL to nuclear speckles. Also localized to Cajal (coiled) bodies.
|
| Tissue Specificity |
Strongly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, prostate, testis, small intestine and colon. Poorly expressed in thymus. {ECO:0000269|PubMed:11418481}.
|