Gene Symbol | PERP |
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Entrez Gene | 64065 |
Alt Symbol | KCP1, KRTCAP1, PIGPC1, THW, dJ496H19.1 |
Species | Human |
Gene Type | protein-coding |
Description | PERP, TP53 apoptosis effector |
Other Description | 1110017A08Rik|KCP-1|keratinocyte associated protein 1|keratinocyte-associated protein 1|keratinocytes associated protein 1|p53 apoptosis effector related to PMP-22|p53 apoptosis effector related to PMP22|p53-induced protein PIGPC1|transmembrane protein THW |
Swissprots | Q9H230 Q8NC16 Q8N1J6 Q9H1C5 Q8IWS3 B2RB73 E1P590 Q96FX8 |
Accessions | CAF85829 CCF76964 EAW47920 EAW47921 Q96FX8 AF317550 AAG35063 AJ251830 CAC17766 AK074585 BAC11074 AK075082 BAC11390 AK093516 BAG52734 AK097387 BAG53462 AK097958 BAC05205 AK225907 AK314526 BAG37120 AY157578 AAO13162 BC010163 AAH10163 BU674771 CA310443 CX784592 DA750046 DQ892670 ABM83596 DR422553 EU176724 ABW03525 NM_022121 NP_071404 |
Function | Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity). {ECO:0000250}. |
Subcellular Location | Cell junction, desmosome. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Associated with desmosomes. {ECO:0000250}. |
Tissue Specificity | Expressed in skin, heart, placental, liver, pancreas, keratinocytes and dermal fibroblasts. {ECO:0000269|PubMed:12752121}. |
Top Pathways | p53 signaling pathway |
Human PERP full length protein - ab131934 from Abcam
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Human PERP peptide - ab39843 from Abcam
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PERP peptide - ab48071 from Abcam
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PERP Antibody Blocking Peptide - LS-E3338 from LifeSpan Bioscience
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PERP Antibody Blocking Peptide - LS-E17934 from LifeSpan Bioscience
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PERP Antibody Blocking Peptide - LS-E26090 from LifeSpan Bioscience
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PERP Antibody Blocking Peptide - LS-E29967 from LifeSpan Bioscience
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PERP Recombinant Protein - H00064065-P01 from Novus Biologicals
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PERP Blocking Peptide - NBP1-76741PEP from Novus Biologicals
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PERP-Antibody-C-term-Blocking-Peptide - BP14508b from Abgent, a WuXi AppTec company
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PERP blocking peptide - GTX89344-PEP from GeneTex
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PERP Peptide - GTX85520-PEP from GeneTex
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PERP Immunizing peptide - orb15104 from Biorbyt
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PERP Blocking Peptide - 33R-2984 from Fitzgerald
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PERP Peptide - AC21-0918-P from Abcore
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PERP - H00064065-P01-10 from Acris Antibodies
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PERP - H00064065-P01-25 from Acris Antibodies
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PERP Peptide - 2451P from ProSci
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PERP Peptide - 46-169P from ProSci
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PERP fusion protein - Ag13257 from Proteintech Group
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Recombinant Human PERP, GST-tagged - PERP-1647H from Creative Biomart
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PERP - TP304012 from Acris Antibodies
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PERP, Peptide - MBS426885 from MyBioSource
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PERP Recombinant Protein Antigen - NBP1-85173PEP from Novus Biologicals
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PERP Peptide, Human - M34GP11594H from Creative Peptides
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