Gene Symbol | MED9 |
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Entrez Gene | 55090 |
Alt Symbol | MED25 |
Species | Human |
Gene Type | protein-coding |
Description | mediator complex subunit 9 |
Other Description | mediator of RNA polymerase II transcription subunit 9|mediator of RNA polymerase II transcription, subunit 9 homolog|mediator subunit 25 |
Swissprots | Q9NWA0 |
Accessions | EAW55706 EAW55707 Q9NWA0 AK001055 BAA91483 BC000647 BC010906 BC104988 AAI04989 BC112029 AAI12030 HG518168 CDI06891 NM_018019 NP_060489 |
Function | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Subcellular Location | Nucleus {ECO:0000305}. |
Med9 CRISPR/Cas9 KO Plasmid (h) - sc-412442 from Santa Cruz Biotechnology
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Med9 HDR Plasmid (h) - sc-412442-HDR from Santa Cruz Biotechnology
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Med9 Double Nickase Plasmid (h) - sc-412442-NIC from Santa Cruz Biotechnology
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Med9 Double Nickase Plasmid (h2) - sc-412442-NIC-2 from Santa Cruz Biotechnology
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Med9 CRISPR Activation Plasmid (h) - sc-412442-ACT from Santa Cruz Biotechnology
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Med9 CRISPR Activation Plasmid (h2) - sc-412442-ACT-2 from Santa Cruz Biotechnology
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Med9 Lentiviral Activation Particles (h) - sc-412442-LAC from Santa Cruz Biotechnology
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Med9 Lentiviral Activation Particles (h2) - sc-412442-LAC-2 from Santa Cruz Biotechnology
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Med9 siRNA (h) - sc-94034 from Santa Cruz Biotechnology
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Med9 shRNA Plasmid (h) - sc-94034-SH from Santa Cruz Biotechnology
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Med9 shRNA (h) Lentiviral Particles - sc-94034-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU027491 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN13185 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND13185 from Sigma-Aldrich
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MED9 siRNA (Human) - CRJ0460 from Cohesion Biosciences
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shRNA set against Human MED9 (NM_018019.2) - SHH340163 from Creative biogene
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shRNA set against Human MED9(NM_018019.2) - SHH183791 from Creative biogene
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Human MED9 siRNA - orb270961 from Biorbyt
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MED9 shRNA Plasmid (Human) - CHJ0460 from Cohesion Biosciences
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MED9 miRNA 3'UTR clone - MiUTR1H-06195 from Creative biogene
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