ITPR2

Gene Symbol ITPR2
Entrez Gene 3709
Alt Symbol ANHD, CFAP48, IP3R2
Species Human
Gene Type protein-coding
Description inositol 1,4,5-trisphosphate receptor, type 2
Other Description IP3 receptor|IP3R 2|cilia and flagella associated protein 48|inositol 1,4,5-triphosphate receptor, type 2|inositol 1,4,5-trisphosphate receptor type 2|insP3R2|type 2 InsP3 receptor|type 2 inositol 1,4,5-trisphosphate receptor
Swissprots Q14571 O94773
Accessions AFI41831 EAW96534 EAW96535 Q14571 AB012610 BAA33961 AI339141 AK307686 AK307712 AK310504 AL711179 AY429550 BC172383 AAI72383 BE439696 BP314401 BP364657 BU173910 BX495410 CA419735 D26350 BAA05384 DB144849 XM_011520645 XP_011518947 XM_011520646 XP_011518948 XR_931288 NM_002223 NP_002214
Function Receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. This release is regulated by cAMP both dependently and independently of PKA (By similarity). {ECO:0000250}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Isoform Short is found in skeletal muscle and heart.
Top Pathways Inflammatory mediator regulation of TRP channels, Oxytocin signaling pathway, cGMP-PKG signaling pathway, Thyroid hormone synthesis, Estrogen signaling pathway

Panoply™ Human ITPR2 Knockdown Stable Cell Line - CSC-DC007831 from Creative biogene

Category Cell Line
Species Human
Search more