Gene Symbol | PTDSS1 |
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Entrez Gene | 9791 |
Alt Symbol | LMHD, PSS1, PSSA |
Species | Human |
Gene Type | protein-coding |
Description | phosphatidylserine synthase 1 |
Other Description | PSS-1|ptdSer synthase 1|serine-exchange enzyme I |
Swissprots | B4DE85 P48651 Q9BUQ5 E5RFC5 |
Accessions | EAW91753 EAW91754 P48651 AK293036 BAF85725 AK293513 BAG56996 BC002376 AAH02376 BC004192 AAH04192 BC004390 AAH04390 BC004502 AAH04502 BM459031 D14694 BAA03520 DQ891825 ABM82751 DQ895012 ABM85938 HY087183 NM_001290225 NP_001277154 NM_014754 NP_055569 |
Function | Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. In membranes, PTDSS1 catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Highly enriched in the mitochondria-associated membrane (MAM). {ECO:0000250}. |
Top Pathways | Glycerophospholipid metabolism |
Phosphatidylserine synthase 1 (PTDSS1), Human, ELISA Kit - CSB-EL018962HU from ARP American Research Products
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phosphatidylserine synthase 1, ELISA Kit - MBS908663 from MyBioSource
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Human Phosphatidylserine synthase 1(PTDSS1) ELISA kit - CSB-EL018962HU from Cusabio
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Human Phosphatidylserine synthase 1 (PTDSS1) ELISA Kit - EKC34997 from Biomatik
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Human PTDSS1 ELISA Kit - E029000 from Biobool
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