| Gene Symbol |
ADNP
|
| Entrez Gene |
23394
|
| Alt Symbol |
ADNP1, HVDAS, MRD28
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
activity-dependent neuroprotector homeobox
|
| Other Description |
ADNP homeobox 1|activity-dependent neuroprotective protein|activity-dependent neuroprotector homeobox protein
|
| Swissprots |
O94881 Q9H2P0 Q5BKU2 Q9UG34 E1P5Y2
|
| Accessions |
CAC33127 EAW75611 EAW75612 Q9H2P0 AB018327 BAA34504 AF250860 AAG47651 AK074926 AK314734 BAG37275 AL080163 CAB45752 AW452644 BC015554 BC075794 AAH75794 BC090933 AAH90933 BM998017 DR006081 DR006382 XM_011528747 XP_011527049 XM_011528748 XP_011527050 NM_001282531 NP_001269460 NM_001282532 NP_001269461 NM_015339 NP_056154 NM_181442 NP_852107
|
| Function |
Potential transcription factor. May mediate some of the neuroprotective peptide VIP-associated effects involving normal growth and cancer proliferation.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00108}.
|
| Tissue Specificity |
Widely expressed. Strong expression in heart, skeletal muscle, kidney and placenta. In brain, expression is stronger in the cerebellum and cortex regions. No expression detected in the colon. Strong increase of expression in colon and breast cancer tissues.
|
![Western Blot: ADNP Overexpression Lysate (Adult Normal) [NBL1-07346] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ADNP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8880_ADNP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-07346-img0002.jpg)
![Western Blot: ADNP Overexpression Lysate (Adult Normal) [NBP2-04923] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ADNP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4172_ADNP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-04923-img0001.jpg)
![Western Blot: ADNP Overexpression Lysate (Adult Normal) [NBP2-10045] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for ADNP.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5424_ADNP%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-10045-img0001.jpg)