GFM2
| Gene Symbol | GFM2 |
|---|---|
| Entrez Gene | 84340 |
| Alt Symbol | EF-G2mt, EFG2, MRRF2, MST027, MSTP027, RRF2, RRF2mt, hEFG2, mEF-G 2 |
| Species | Human |
| Gene Type | protein-coding |
| Description | G elongation factor, mitochondrial 2 |
| Other Description | EF-G2mt|RRF2mt|mEF-G 2|mitochondrial elongation factor G2|mitochondrial ribosome recycling factor 2|ribosome-releasing factor 2, mitochondrial |
| Swissprots | Q8N6D8 Q969S9 Q8WYI0 A0AR28 Q9H6Z1 |
| Accessions | EAW95743 EAW95744 EAW95745 EAW95746 EAW95747 EAW95748 Q969S9 AA418187 AF111808 AAL39010 AF367997 AAK53401 AK025314 BAB15109 AK307839 AK308422 AK315705 AY453587 AAS49035 BC015712 AAH15712 BC030612 AAH30612 BI828937 BU622328 DC402212 JF432829 ADZ16046 XM_006714721 XP_006714784 XM_011543690 XP_011541992 XM_011543691 XP_011541993 NM_001281302 NP_001268231 NM_032380 NP_115756 NM_170681 NP_733781 NM_170691 NP_733792 NR_104006 |
| Function | Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. {ECO:0000255|HAMAP-Rule:MF_03059, ECO:0000269|PubMed:19716793}. |
| Subcellular Location | Mitochondrion {ECO:0000255|HAMAP- Rule:MF_03059}. |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:11735030}. |
EF-G2 CRISPR/Cas9 KO Plasmid (h) - sc-413635 from Santa Cruz Biotechnology
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EF-G2 HDR Plasmid (h) - sc-413635-HDR from Santa Cruz Biotechnology
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EF-G2 Double Nickase Plasmid (h) - sc-413635-NIC from Santa Cruz Biotechnology
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EF-G2 Double Nickase Plasmid (h2) - sc-413635-NIC-2 from Santa Cruz Biotechnology
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EF-G2 CRISPR Activation Plasmid (h) - sc-413635-ACT from Santa Cruz Biotechnology
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EF-G2 CRISPR Activation Plasmid (h2) - sc-413635-ACT-2 from Santa Cruz Biotechnology
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EF-G2 Lentiviral Activation Particles (h) - sc-413635-LAC from Santa Cruz Biotechnology
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EF-G2 Lentiviral Activation Particles (h2) - sc-413635-LAC-2 from Santa Cruz Biotechnology
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EF-G2 siRNA (h) - sc-91850 from Santa Cruz Biotechnology
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EF-G2 shRNA Plasmid (h) - sc-91850-SH from Santa Cruz Biotechnology
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EF-G2 shRNA (h) Lentiviral Particles - sc-91850-V from Santa Cruz Biotechnology
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GFM2 RNAi - H00084340-R02 from Novus Biologicals
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GFM2 RNAi - H00084340-R01 from Novus Biologicals
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MISSION® esiRNA - EHU063481 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9242 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9242 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03451 from Sigma-Aldrich
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GFM2 siRNA (Human) - CRJ3457 from Cohesion Biosciences
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GFM2 RNAi - H00084340-R03 from Novus Biologicals
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GFM2 - MBS8220390 from MyBioSource
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shRNA set against Human GFM2 (NM_032380.3) - SHH300602 from Creative biogene
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shRNA set against Human GFM2(NM_170691.1) - SHH082343 from Creative biogene
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shRNA set against Human GFM2(NM_032380.3) - SHH082361 from Creative biogene
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shRNA set against Human GFM2(NM_170681.1) - SHH082397 from Creative biogene
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Human GFM2 siRNA - orb273958 from Biorbyt
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