| Gene Symbol | ACPT |
|---|---|
| Entrez Gene | 93650 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | acid phosphatase, testicular |
| Other Description | testicular acid phosphatase |
| Swissprots | C0H3P7 Q9BZG2 Q9BZG4 Q9BZG3 |
| Accessions | AAK09393 AAK09394 AAK09395 AAK09396 EAW71900 EAW71901 EAW71902 EAW71903 EAW71904 Q9BZG2 BC140294 AAI40295 BC146506 AAI46507 NM_033068 NP_149059 NM_080789 NM_080790 NM_080791 |
| Function | Dephosphorylates receptor tyrosine-protein kinase erbB-4 and inhibits the ligand-induced proteolytic cleavage. {ECO:0000269|PubMed:15219672}. |
| Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Tissue Specificity | Expressed mainly in the testis. Also expressed in the brain where they are enriched at the postsynaptic sites. Expressed at lower levels in the trachea, prostate, bone marrow, spinal cord, colon, fetal brain, heart, thymus, fetal liver, spleen, leukocytes, ovary, small intestine, pancreas and skeletal muscle. Expression is significantly lower in testicular cancer tissues than in normal testicular tissues. Isoform 3 is expressed in the testis, trachea, prostate and bone marrow. {ECO:0000269|PubMed:11414767}. |
| Top Pathways | Riboflavin metabolism |
Human ACPT ORF clone (NM_033068.2) - CDCR023968 from Creative biogene
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Human ACPT cDNA Clone(NM_033068.2) - CDFG006587 from Creative biogene
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