Gene Symbol | CORT |
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Entrez Gene | 1325 |
Alt Symbol | CST-14, CST-17, CST-29 |
Species | Human |
Gene Type | protein-coding |
Description | cortistatin |
Other Description | cortistatin-14|cortistatin-17|cortistatin-29|prepro-cortistatin|preprocortistatin |
Swissprots | O00230 Q6UX11 Q5T6G0 |
Accessions | EAW71650 O00230 AB000263 BAA19770 AF013252 AAB66895 AF086433 AV750349 AW205880 AY358561 AAQ89950 BC040034 AAH40034 BC119724 AAI19725 BC119725 AAI19726 BF590359 NM_001302 NP_001293 |
Function | Binds to all human somatostatin receptor (SSTR) subtypes. It also inhibits cAMP production induced by forskolin through SSTRs. |
Subcellular Location | Secreted. |
Tissue Specificity | Expressed in a subset of GABAergic cells in the cortex and hippocampus. |
cortistatin CRISPR/Cas9 KO Plasmid (h) - sc-417234 from Santa Cruz Biotechnology
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cortistatin HDR Plasmid (h) - sc-417234-HDR from Santa Cruz Biotechnology
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cortistatin Double Nickase Plasmid (h) - sc-417234-NIC from Santa Cruz Biotechnology
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cortistatin Double Nickase Plasmid (h2) - sc-417234-NIC-2 from Santa Cruz Biotechnology
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cortistatin CRISPR Activation Plasmid (h) - sc-417234-ACT from Santa Cruz Biotechnology
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cortistatin CRISPR Activation Plasmid (h2) - sc-417234-ACT-2 from Santa Cruz Biotechnology
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cortistatin Lentiviral Activation Particles (h) - sc-417234-LAC from Santa Cruz Biotechnology
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cortistatin Lentiviral Activation Particles (h2) - sc-417234-LAC-2 from Santa Cruz Biotechnology
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cortistatin siRNA (h) - sc-39726 from Santa Cruz Biotechnology
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cortistatin shRNA Plasmid (h) - sc-39726-SH from Santa Cruz Biotechnology
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cortistatin shRNA (h) Lentiviral Particles - sc-39726-V from Santa Cruz Biotechnology
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Cortistatin RNAi - H00001325-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN6460 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6460 from Sigma-Aldrich
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CORT siRNA (Human) - CRH0930 from Cohesion Biosciences
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CORT - MBS827491 from MyBioSource
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shRNA set against Human CORT (NM_001302.4) - SHH268129 from Creative biogene
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CORT shRNA Plasmid (Human) - CHH0930 from Cohesion Biosciences
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CORT miRNA 3'UTR clone - MiUTR4H-TG02297 from Creative biogene
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