Gene Symbol | Nsf |
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Entrez Gene | 18195 |
Alt Symbol | AI316878, AU020090, AU067812, SKD2 |
Species | Mouse |
Gene Type | protein-coding |
Description | N-ethylmaleimide sensitive fusion protein |
Other Description | N-ethylmaleimide sensitive factor|N-ethylmaleimide-sensitive fusion protein|NEM-sensitive fusion protein|suppressor of K(+) transport growth defect 2|vesicle-fusing ATPase|vesicular-fusion protein NSF |
Swissprots | A2A646 P46460 Q8CCT9 Q8CEF0 Q8BQ65 Q923C6 Q8C3R2 |
Accessions | EDL34203 EDL34204 P46460 AK028415 BAC25937 AK032120 BAC27713 AK042341 AK049281 BAC33656 AK051430 BAC34637 AK085086 BAC39361 AK141986 AK153905 BAE32247 AK181330 AK188021 AK197119 AK198098 AK203353 AK206182 AK208406 AK208793 AK213251 AK214505 AK216127 BC006627 AAH06627 BC019167 AAH19167 U10120 AAA50498 NM_008740 NP_032766 |
Function | Required for vesicle-mediated transport. Catalyzes the fusion of transport vesicles within the Golgi cisternae. Is also required for transport from the endoplasmic reticulum to the Golgi stack. Seems to function as a fusion protein required for the delivery of cargo proteins to all compartments of the Golgi stack GRIA2 leads to influence GRIA2 membrane cycling (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. |
Top Pathways | Vasopressin-regulated water reabsorption, Synaptic vesicle cycle, GABAergic synapse |
NSF CRISPR/Cas9 KO Plasmid (m) - sc-421972 from Santa Cruz Biotechnology
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NSF HDR Plasmid (m) - sc-421972-HDR from Santa Cruz Biotechnology
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NSF Double Nickase Plasmid (m) - sc-421972-NIC from Santa Cruz Biotechnology
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NSF Double Nickase Plasmid (m2) - sc-421972-NIC-2 from Santa Cruz Biotechnology
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NSF CRISPR Activation Plasmid (m) - sc-421972-ACT from Santa Cruz Biotechnology
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NSF CRISPR Activation Plasmid (m2) - sc-421972-ACT-2 from Santa Cruz Biotechnology
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NSF Lentiviral Activation Particles (m) - sc-421972-LAC from Santa Cruz Biotechnology
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NSF Lentiviral Activation Particles (m2) - sc-421972-LAC-2 from Santa Cruz Biotechnology
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NSF siRNA (m) - sc-36102 from Santa Cruz Biotechnology
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NSF shRNA Plasmid (m) - sc-36102-SH from Santa Cruz Biotechnology
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NSF shRNA (m) Lentiviral Particles - sc-36102-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU075681 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN36706 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND36706 from Sigma-Aldrich
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NSF siRNA (Mouse) - CRM2848 from Cohesion Biosciences
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shRNA set against Mouse NSF (NM_008740.4) - SHH355336 from Creative biogene
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shRNA set against Mouse Nsf(NM_008740.4) - SHR023128 from Creative biogene
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NSF shRNA Plasmid (Mouse) - CHM2848 from Cohesion Biosciences
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NSF miRNA 3'UTR clone - MiUTR1M-07840 from Creative biogene
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