CDC20

Gene Symbol	CDC20
Entrez Gene	991
Alt Symbol	CDC20A, bA276H19.3, p55CDC
Species	Human
Gene Type	protein-coding
Description	cell division cycle 20
Other Description	CDC20 cell division cycle 20 homolog|cell division cycle 20 homolog|cell division cycle protein 20 homolog
Swissprots	Q12834 Q9BW56 B2R6Z6 Q9UQI9 D3DPJ1 Q5JUY4
Accessions	ABE96834 EAX07101 EAX07102 Q12834 AF099644 AAD16405 AK225504 AK302539 BAG63811 AK303844 BAG64787 AK312780 BAG35643 BC000624 AAH00624 BC001088 AAH01088 BC006272 AAH06272 BC009425 AAH09425 BC009426 AAH09426 BC010044 AAH10044 BC012803 AAH12803 BC012827 AAH12827 BC013303 AAH13303 BC015998 AAH15998 BC024257 AAH24257 BC031294 AAH31294 BC110321 AAI10322 BT007388 AAP36052 DQ892290 ABM83216 DQ895489 ABM86415 EU831627 ACE87227 EU831712 ACE86546 U05340 AAA19017 NM_001255 NP_001246
Function	Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. {ECO:0000269|PubMed:9637688, ECO:0000269|PubMed:9734353, ECO:0000269|PubMed:9811605}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20034488}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:20034488}.
Top Pathways	Cell cycle, Ubiquitin mediated proteolysis, Oocyte meiosis, HTLV-I infection, Viral carcinogenesis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Cdc20 full length protein - ab131769 from Abcam Category Protein Prices $402.00 Sizes 2 µg Source Wheat germ Species Human

Human Cdc20 peptide - ab28139 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human Cdc20 protein fragment - ab114348 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

CDC20 Antibody Blocking Peptide - LS-E10521 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CDC20 Antibody Blocking Peptide - LS-E9961 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Cdc20 Protein - H00000991-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Cdc20 Protein - H00000991-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

CDC20-Antibody-N-term-Blocking-Peptide - BP9138a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CDC20 Blocking Peptide - 33R-5724 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

CDC20 Blocking Peptide - abx062386 from Abbexa Category Peptide Species Human, Monkey, Pig

CDC20 - H00000991-P01 from Acris Antibodies Category Protein Prices $340.00 Sizes 2 µg Species Human

CDC20 - H00000991-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CDC20 - H00000991-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

CDC20 - H00000991-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CDC20 - H00000991-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CDC20 fusion protein - ag0295 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CDC20 - CDC20-27897TH from Creative Biomart Category Protein Source Wheat germ

CDC20 Blocking Peptide - CBP1192 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Monkey, Pig

Cdc20 (Q105) Peptide - BS2203P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Cell division cycle protein 20 homolog(CDC20) - CSB-YP623655HU CSB-EP623655HU CSB-BP623655HU CSB-MP623655HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

CDC20 - TP300911 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Cell division cycle protein 20 homolog (CDC20), Recombinant Protein - MBS1290745 from MyBioSource Category Protein Prices $1,285.00, $1,285.00, $1,505.00, $1,505.00, $2,110.00, $2,110.00, $2,575.00, $2,575.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Cdc20 Recombinant Protein Antigen - NBP2-38750PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

CDC20 Peptide, Human - M34GP02793H from Creative Peptides Category Peptide Source Synthetic. Species Human

Cdc20 Recombinant Protein Antigen - NBP2-58408PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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