Gene Symbol | BRI3BP |
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Entrez Gene | 140707 |
Alt Symbol | BNAS1, HCCR-1, HCCR-2, HCCRBP-1, KG19 |
Species | Human |
Gene Type | protein-coding |
Description | BRI3 binding protein |
Other Description | BRI3-binding protein|I3-binding protein|cervical cancer 1 proto-oncogene-binding protein KG19|cervical cancer oncogene binding protein |
Swissprots | Q8WY23 Q8WY22 |
Accessions | EAW98470 EAW98471 Q8WY22 AF283671 AAL33003 AF284094 AAL54382 AF441865 AAN76689 AK055703 BC034525 AAH34525 CA488612 XM_011537940 XP_011536242 NM_080626 NP_542193 |
Function | Involved in tumorigenesis and may function by stabilizing p53/TP53. {ECO:0000269|PubMed:17943721}. |
Subcellular Location | Mitochondrion outer membrane {ECO:0000305|PubMed:17943721}; Multi-pass membrane protein {ECO:0000305|PubMed:17943721}. |
Tissue Specificity | Most abundantly expressed in brain, liver and kidney. Overexpressed in leukemia and lymphoma cell lines, as well as in various carcinomas. {ECO:0000269|PubMed:11860200, ECO:0000269|PubMed:17943721}. |
BRI3BP CRISPR/Cas9 KO Plasmid (h) - sc-407160 from Santa Cruz Biotechnology
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BRI3BP HDR Plasmid (h) - sc-407160-HDR from Santa Cruz Biotechnology
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BRI3BP Double Nickase Plasmid (h) - sc-407160-NIC from Santa Cruz Biotechnology
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BRI3BP Double Nickase Plasmid (h2) - sc-407160-NIC-2 from Santa Cruz Biotechnology
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BRI3BP CRISPR Activation Plasmid (h) - sc-407160-ACT from Santa Cruz Biotechnology
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BRI3BP CRISPR Activation Plasmid (h2) - sc-407160-ACT-2 from Santa Cruz Biotechnology
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BRI3BP Lentiviral Activation Particles (h) - sc-407160-LAC from Santa Cruz Biotechnology
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BRI3BP Lentiviral Activation Particles (h2) - sc-407160-LAC-2 from Santa Cruz Biotechnology
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BRI3BP siRNA (h) - sc-95884 from Santa Cruz Biotechnology
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BRI3BP shRNA Plasmid (h) - sc-95884-SH from Santa Cruz Biotechnology
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BRI3BP shRNA (h) Lentiviral Particles - sc-95884-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU151611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4061 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4061 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12064 from Sigma-Aldrich
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BRI3BP siRNA (Human) - CRJ5309 from Cohesion Biosciences
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BRI3BP - MBS8219216 from MyBioSource
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shRNA set against Human BRI3BP (NM_080626.5) - SHH247730 from Creative biogene
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shRNA set against Human BRI3BP(NM_080626.5) - SHG104959 from Creative biogene
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Human BRI3BP siRNA - orb275810 from Biorbyt
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BRI3BP shRNA Plasmid (Human) - CHJ5309 from Cohesion Biosciences
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BRI3BP miRNA 3'UTR clone - MiUTR1H-00945 from Creative biogene
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