Gene Symbol | FAF2 |
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Entrez Gene | 23197 |
Alt Symbol | ETEA, UBXD8, UBXN3B |
Species | Human |
Gene Type | protein-coding |
Description | Fas associated factor family member 2 |
Other Description | FAS-associated factor 2|UBX domain containing 8|UBX domain protein 3B|UBX domain-containing protein 3B|UBX domain-containing protein 8|expressed in T-cells and eosinophils in atopic dermatitis |
Swissprots | O94963 Q96CS3 Q9BRP2 Q9BVM7 Q8IUF2 |
Accessions | EAW85073 EAW85074 EAW85075 Q96CS3 AB020694 BAA74910 AB088120 BAC22491 AK304346 BAG65190 AL706430 BC001069 AAH01069 BC006145 AAH06145 BC014001 AAH14001 BC015791 BC021065 DQ892700 ABM83626 DQ896293 ABM87292 XM_011534475 XP_011532777 XM_011534476 XP_011532778 NM_014613 NP_055428 |
Function | May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome. {ECO:0000269|PubMed:18711132}. |
Subcellular Location | Cytoplasm. Lipid droplet. Endoplasmic reticulum. |
Tissue Specificity | Broadly expressed, with highest levels in brain. {ECO:0000269|PubMed:12372427}. |
ETEA CRISPR/Cas9 KO Plasmid (h) - sc-403730 from Santa Cruz Biotechnology
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ETEA HDR Plasmid (h) - sc-403730-HDR from Santa Cruz Biotechnology
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ETEA Double Nickase Plasmid (h) - sc-403730-NIC from Santa Cruz Biotechnology
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ETEA Double Nickase Plasmid (h2) - sc-403730-NIC-2 from Santa Cruz Biotechnology
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ETEA CRISPR Activation Plasmid (h) - sc-403730-ACT from Santa Cruz Biotechnology
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ETEA CRISPR Activation Plasmid (h2) - sc-403730-ACT-2 from Santa Cruz Biotechnology
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ETEA Lentiviral Activation Particles (h) - sc-403730-LAC from Santa Cruz Biotechnology
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ETEA Lentiviral Activation Particles (h2) - sc-403730-LAC-2 from Santa Cruz Biotechnology
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ETEA siRNA (h) - sc-60607 from Santa Cruz Biotechnology
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ETEA shRNA Plasmid (h) - sc-60607-SH from Santa Cruz Biotechnology
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ETEA shRNA (h) Lentiviral Particles - sc-60607-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU025301 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN8095 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND8095 from Sigma-Aldrich
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FAF2 siRNA (Human) - CRH8077 from Cohesion Biosciences
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FAF2 - MBS8217768 from MyBioSource
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shRNA set against Human FAF2 (NM_014613.2) - SHH288769 from Creative biogene
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shRNA set against Human UBXD8(NM_014613.2) - SHL104300 from Creative biogene
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FAF2 shRNA Plasmid (Human) - CHH8077 from Cohesion Biosciences
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FAF2 miRNA 3'UTR clone - MiUTR1H-10977 from Creative biogene
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