Gene Symbol | FASN |
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Entrez Gene | 2194 |
Alt Symbol | FAS, OA-519, SDR27X1 |
Species | Human |
Gene Type | protein-coding |
Description | fatty acid synthase |
Other Description | short chain dehydrogenase/reductase family 27X, member 1 |
Swissprots | Q13479 Q969R1 P49327 Q4LE83 Q96C68 Q6P4U5 Q6SS02 Q16702 Q96IT0 |
Accessions | AAC50536 EAW89745 P49327 AB209988 BAE06070 AY451392 AAS09886 BC007267 AAH07267 BC007305 BC007909 AAH07909 BC014631 AAH14631 BC014634 AAH14634 BC021544 BC063242 AAH63242 S80437 AAB35516 U26644 AAC50259 U29344 AAA73576 XM_011523538 XP_011521840 NM_004104 NP_004095 |
Function | Fatty acid synthetase catalyzes the formation of long- chain fatty acids from acetyl-CoA, malonyl-CoA and NADPH. This multifunctional protein has 7 catalytic activities and an acyl carrier protein. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17081065}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
Tissue Specificity | Ubiquitous. Prominent expression in brain, lung, and liver. {ECO:0000269|PubMed:7567999, ECO:0000269|PubMed:7595075}. |
Top Pathways | Insulin signaling pathway, AMPK signaling pathway, Fatty acid biosynthesis, Fatty acid metabolism |
Human Fatty Acid Synthase full length protein - ab131929 from Abcam
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Mouse Fatty Acid Synthase peptide - ab25719 from Abcam
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FASN / Fatty Acid Synthase Antibody Blocking Peptide - LS-E8964 from LifeSpan Bioscience
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Recombinant Human Fatty Acid Synthase/FASN Protein - H00002194-P01 from Novus Biologicals
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Recombinant Human Fatty Acid Synthase/FASN Protein - H00002194-Q01 from Novus Biologicals
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FASN-Antibody-Center-Blocking-Peptide - BP7449c from Abgent, a WuXi AppTec company
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Recombinant human Fatty acid synthase (OPCA00980) - OPCA00980 from Aviva Systems Biology
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Human FASN FAS protein - orb245551 from Biorbyt
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FASN Blocking Peptide - abx062608 from Abbexa
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Human Fatty Acid Synthase Protein - abx066535 from Abbexa
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Fatty acid synthase - H00002194-P01-10 from Acris Antibodies
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Fatty acid synthase - H00002194-P01-25 from Acris Antibodies
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Fatty acid synthase - H00002194-Q01-10 from Acris Antibodies
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Fatty acid synthase - H00002194-Q01-25 from Acris Antibodies
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FASN fusion protein - Ag0975 from Proteintech Group
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Recombinant Human FASN, His-tagged - FASN-28809TH from Creative Biomart
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Recombinant Human FASN, GST-tagged - FASN-20H from Creative Biomart
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Recombinant Human FASN, GST-tagged - FASN-21H from Creative Biomart
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Recombinant Human FASN - FASN-468H from Creative Biomart
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Recombinant Fatty Acid Synthase (FASN) - RPC470Hu01 from Uscn Life Science Inc.
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Recombinant Fatty Acid Synthase (FASN) - RPC470Mu01 from Uscn Life Science Inc.
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Recombinant Fatty Acid Synthase (FASN) - RPC470Mu02 from Uscn Life Science Inc.
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Recombinant Fatty Acid Synthase (FASN) - RPC470Ra01 from Uscn Life Science Inc.
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Recombinant Fatty Acid Synthase (FASN) - RPC470Ga01 from Uscn Life Science Inc.
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FASN Blocking Peptide - CBP1414 from Cohesion Biosciences
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