Gene Symbol | SYNPO |
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Entrez Gene | 11346 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | synaptopodin |
Other Description | - |
Swissprots | O15271 Q9UPX1 D3DQG8 A5PKZ8 Q8N3V7 |
Accessions | AAQ07404 EAW61715 EAW61716 Q8N3V7 AA303936 AB028952 BAA82981 AF499136 AAQ07402 AF499137 AAQ07403 AJ278122 AK091066 AK095279 AK127049 BAG54430 AK290178 BAF82867 AL049298 AL049959 AL831818 CAD38532 AM392825 CAL37703 AM393443 CAL38321 BC042624 BC113927 BC114512 BC142683 AAI42684 BC146665 AAI46666 BC152538 AAI52539 BP237193 DA333058 F30246 Y11072 CAA71955 XM_005268369 XP_005268426 XM_005268370 XP_005268427 XM_005268371 XP_005268428 XM_006714755 XP_006714818 XM_011537552 XP_011535854 NM_001109974 NP_001103444 NM_001166208 NP_001159680 NM_001166209 NP_001159681 NM_007286 NP_009217 |
Function | Actin-associated protein that may play a role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. Seems to be essential for the formation of spine apparatuses in spines of telencephalic neurons, which is involved in synaptic plasticity (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm, cytoskeleton {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Perikaryon {ECO:0000250}. Cell projection, dendritic spine {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Note=Localized at the tight junction of cells. In brain, localized to the postsynaptic densities and in the perikarya. Associated with dendritic spines of a subset of synapses (By similarity). {ECO:0000250}. |
Tissue Specificity | Expressed in cerebral cortex. {ECO:0000269|PubMed:9314539}. |
Synaptopodin CRISPR/Cas9 KO Plasmid (h) - sc-400486 from Santa Cruz Biotechnology
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Synaptopodin HDR Plasmid (h) - sc-400486-HDR from Santa Cruz Biotechnology
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Synaptopodin Double Nickase Plasmid (h) - sc-400486-NIC from Santa Cruz Biotechnology
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Synaptopodin Double Nickase Plasmid (h2) - sc-400486-NIC-2 from Santa Cruz Biotechnology
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Synaptopodin CRISPR Activation Plasmid (h) - sc-400486-ACT from Santa Cruz Biotechnology
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Synaptopodin CRISPR Activation Plasmid (h2) - sc-400486-ACT-2 from Santa Cruz Biotechnology
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Synaptopodin Lentiviral Activation Particles (h) - sc-400486-LAC from Santa Cruz Biotechnology
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Synaptopodin Lentiviral Activation Particles (h2) - sc-400486-LAC-2 from Santa Cruz Biotechnology
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Synaptopodin siRNA (h) - sc-44134 from Santa Cruz Biotechnology
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Synaptopodin shRNA Plasmid (h) - sc-44134-SH from Santa Cruz Biotechnology
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Synaptopodin shRNA (h) Lentiviral Particles - sc-44134-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU133661 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20902 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20902 from Sigma-Aldrich
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SYNPO siRNA (Human) - CRH7773 from Cohesion Biosciences
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SYNPO - MBS8213948 from MyBioSource
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shRNA set against Human SYNPO (NM_007286.5) - SHH421804 from Creative biogene
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Human SYNPO siRNA - orb268275 from Biorbyt
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SYNPO shRNA Plasmid (Human) - CHH7773 from Cohesion Biosciences
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SYNPO miRNA 3'UTR clone - MiUTR4H-TG08706 from Creative biogene
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