Gene Symbol | Apoe |
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Entrez Gene | 11816 |
Alt Symbol | AI255918, Apo-E |
Species | Mouse |
Gene Type | protein-coding |
Description | apolipoprotein E |
Other Description | - |
Swissprots | P08226 |
Accessions | BAA00361 EDL23176 EDL23177 EDL23178 EDL23179 EDL23180 EDL23181 EDL23182 EDL23183 EDL23184 P08226 AI836733 AK010261 AK019319 AK075843 BAC36000 AK131624 AK134921 BAE22338 AK148747 AK149111 BAE28740 AK149568 BAE28964 AK150834 BAE29894 AK159105 BAE34821 AK159424 BAE35071 AK159517 BAE35147 AK197774 AK210317 BC028816 AAH28816 BC044785 BC083351 AAH83351 BY313639 BY772289 CT010212 CAJ18420 CT010356 CAJ18564 DN173921 M12414 AAA37251 M73490 AAA37252 NM_001305819 NP_001292748 NM_001305843 NP_001292772 NM_001305844 NP_001292773 NM_009696 NP_033826 |
Function | Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. |
Subcellular Location | Secreted. |
Tissue Specificity | Secreted in plasma. |
Top Pathways | Alzheimer's disease |
apoE CRISPR/Cas9 KO Plasmid (m) - sc-419167 from Santa Cruz Biotechnology
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apoE HDR Plasmid (m) - sc-419167-HDR from Santa Cruz Biotechnology
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apoE Double Nickase Plasmid (m) - sc-419167-NIC from Santa Cruz Biotechnology
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apoE Double Nickase Plasmid (m2) - sc-419167-NIC-2 from Santa Cruz Biotechnology
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apoE CRISPR Activation Plasmid (m) - sc-419167-ACT from Santa Cruz Biotechnology
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apoE CRISPR Activation Plasmid (m2) - sc-419167-ACT-2 from Santa Cruz Biotechnology
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apoE Lentiviral Activation Particles (m) - sc-419167-LAC from Santa Cruz Biotechnology
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apoE Lentiviral Activation Particles (m2) - sc-419167-LAC-2 from Santa Cruz Biotechnology
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apoE siRNA (m) - sc-29709 from Santa Cruz Biotechnology
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apoE shRNA Plasmid (m) - sc-29709-SH from Santa Cruz Biotechnology
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apoE shRNA (m) Lentiviral Particles - sc-29709-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU031371 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26851 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26851 from Sigma-Aldrich
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APOE siRNA (Mouse) - CRM0224 from Cohesion Biosciences
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APOE - MBS8211979 from MyBioSource
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shRNA set against Mouse APOE (NM_009696.3) - SHH238546 from Creative biogene
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shRNA set against Mouse Apoe(NM_009696.3) - SHG065809 from Creative biogene
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apoE CRISPR/Cas9 KO Plasmid (m2) - sc-419167-KO-2 from Santa Cruz Biotechnology
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apoE HDR Plasmid (m2) - sc-419167-HDR-2 from Santa Cruz Biotechnology
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Mouse Apolipoprotein E siRNA - orb279700 from Biorbyt
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APOE shRNA Plasmid (Mouse) - CHM0224 from Cohesion Biosciences
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APOE miRNA 3'UTR clone - MiUTR1M-01589 from Creative biogene
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