Gene Symbol | BCL9L |
---|---|
Entrez Gene | 283149 |
Alt Symbol | BCL9-2, DLNB11 |
Species | Human |
Gene Type | protein-coding |
Description | B-cell CLL/lymphoma 9-like |
Other Description | B-cell CLL/lymphoma 9-like protein|B-cell lymphoma 9-like protein|BCL9-like protein|nuclear co-factor of beta-catenin signalling|protein BCL9-2 |
Swissprots | Q6ZWK2 Q86UU0 A1A4C1 Q67FY1 Q6ZWJ0 |
Accessions | EAW67418 Q86UU0 AB094091 BAC76045 AK122650 BAC85500 AK122882 BAC85512 AY296059 AAQ62697 BC033257 AAH33257 BC156197 AAI56198 XM_005271511 XP_005271568 XM_005271512 XP_005271569 XM_005271513 XP_005271570 XM_006718815 XP_006718878 XM_011542756 XP_011541058 NM_182557 NP_872363 |
Function | Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:17129358, ECO:0000269|PubMed:17309600}. |
Tissue Specificity | Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor. {ECO:0000269|PubMed:12964048, ECO:0000269|PubMed:17129358, ECO:0000269|PubMed:17309600}. |
Bcl-9L CRISPR/Cas9 KO Plasmid (h) - sc-415290 from Santa Cruz Biotechnology
|
||||||||
Bcl-9L HDR Plasmid (h) - sc-415290-HDR from Santa Cruz Biotechnology
|
||||||||
Bcl-9L Double Nickase Plasmid (h) - sc-415290-NIC from Santa Cruz Biotechnology
|
||||||||
Bcl-9L Double Nickase Plasmid (h2) - sc-415290-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Bcl-9L CRISPR Activation Plasmid (h) - sc-415290-ACT from Santa Cruz Biotechnology
|
||||||||
Bcl-9L CRISPR Activation Plasmid (h2) - sc-415290-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Bcl-9L Lentiviral Activation Particles (h) - sc-415290-LAC from Santa Cruz Biotechnology
|
||||||||
Bcl-9L Lentiviral Activation Particles (h2) - sc-415290-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Bcl-9L siRNA (h) - sc-96389 from Santa Cruz Biotechnology
|
||||||||
Bcl-9L shRNA Plasmid (h) - sc-96389-SH from Santa Cruz Biotechnology
|
||||||||
Bcl-9L shRNA (h) Lentiviral Particles - sc-96389-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU054121 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3924 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3924 from Sigma-Aldrich
|
||||||||
BCL9L siRNA (Human) - CRJ6870 from Cohesion Biosciences
|
||||||||
BCL9-2 RNAi - H00283149-R01 from Novus Biologicals
|
||||||||
BCL9L - MBS8208611 from MyBioSource
|
||||||||
shRNA set against Human Bcl9l (NM_182557.2) - SHH246086 from Creative biogene
|
||||||||
shRNA set against Human BCL9L(NM_182557.2) - SHG098143 from Creative biogene
|
||||||||
BCL9L shRNA Plasmid (Human) - CHJ6870 from Cohesion Biosciences
|
||||||||
BCL9L miRNA 3'UTR clone - MiUTR1H-00854 from Creative biogene
|