Gene Symbol | SFRP2 |
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Entrez Gene | 6423 |
Alt Symbol | FRP-2, SARP1, SDF-5 |
Species | Human |
Gene Type | protein-coding |
Description | secreted frizzled-related protein 2 |
Other Description | SARP-1|sFRP-2|secreted apoptosis related protein 1|secreted apoptosis-related protein 1 |
Swissprots | Q9HAP5 Q96HF1 O14778 B3KQR2 |
Accessions | CAZ76869 EAX04949 Q96HF1 AA449032 AF017986 AAB70792 AF311912 AAG24923 AK075372 BAG52124 AK093922 BAG52787 AY359001 AAQ89360 BC008666 AAH08666 BM906663 BM924815 BQ130455 CN431016 NM_003013 NP_003004 |
Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis. |
Subcellular Location | Secreted {ECO:0000250}. |
Tissue Specificity | Expressed in adipose tissue, heart, brain, skeletal muscle, pancreas, thymus, prostate, testis, ovary, small intestine and colon. Highest levels in adipose tissue, small intestine and colon. {ECO:0000269|PubMed:9391078, ECO:0000269|PubMed:9642118}. |
Top Pathways | Wnt signaling pathway |
Human SFRP2 full length protein - ab153777 from Abcam
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SFRP2 Antibody Blocking Peptide - LS-E26267 from LifeSpan Bioscience
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SFRP2-Antibody-C-term-Blocking-peptide - BP12351b from Abgent, a WuXi AppTec company
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SFRP2 blocking peptide - GTX89043-PEP from GeneTex
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Recombinant Human sFRP-2 - 6838-FR-025 from R&D Systems
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Recombinant Human sFRP-2, CF - 6838-FR-025/CF from R&D Systems
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Human sFRP2 protein - orb49632 from Biorbyt
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SFRP2 Blocking Peptide - 33R-2142 from Fitzgerald
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SFRP2 Blocking Peptide - abx063251 from Abbexa
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SFRP2 Peptide - AC21-1099-P from Abcore
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SFRP2 (20-295, His-tag) - AR51426PU-N from Acris Antibodies
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SFRP2 (20-295, His-tag) - AR51426PU-S from Acris Antibodies
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Secreted Frizzled-Related Protein 2, sFRP-2, Human, Recombinant - 19-C640 from ARP American Research Products
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SFRP2, 20-295aa Human, His tag, E.coli - 01-P2606 from ARP American Research Products
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SFRP2 Peptide - 46-712P from ProSci
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SFRP2 fusion protein - ag18840 from Proteintech Group
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SFRP2 fusion protein - Ag2853 from Proteintech Group
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Recombinant Human sFRP2 Protein - BP001409-C640 from Syd Labs
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SFRP2, 20-295aa Human, His tag, E.coli - GWB-ATG0D0 from Genway Biotech
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Recombinant Human SFRP2, His-tagged - SFRP2-7655H from Creative Biomart
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Recombinant Human SFRP2, His-tagged - SFRP2-5110H from Creative Biomart
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Recombinant Human secreted frizzled-related protein 2, His-tagged - SFRP2-509H from Creative Biomart
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Recombinant Human SFRP2 - SFRP2-299H from Creative Biomart
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Recombinant Secreted Frizzled Related Protein 2 (SFRP2) - RPF879Hu01 from Uscn Life Science Inc.
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Recombinant Secreted Frizzled Related Protein 2 (SFRP2) - RPF879Mu01 from Uscn Life Science Inc.
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