CDC14A

Gene Symbol CDC14A
Entrez Gene 8556
Alt Symbol cdc14, hCDC14
Species Human
Gene Type protein-coding
Description cell division cycle 14A
Other Description CDC10 (cell division cycle 10, S. cerevisiae, homolog)|CDC14 cell division cycle 14 homolog A|dual specificity protein phosphatase CDC14A
Swissprots O43171 O60728 B1AQ15 Q8IXX0 O60727 Q9UNH5 B1AQ14 A6MA65 Q52LH9
Accessions AAT38107 EAW72956 EAW72957 EAW72958 EAW72959 EAW72960 Q9UNH5 AA929031 AB209857 BAD93094 AF000367 AAB88277 AF064102 AAC16659 AF064103 AAC16660 AF122013 AAD49217 AK302310 BAG63648 AK310292 AK310657 BC038979 AAH38979 BC071578 BC093916 AAH93916 BC093918 AAH93918 BU609013 CB156695 DA461435 DA885382 DQ530256 ABF74568 XM_005271294 XP_005271351 XM_005271296 XP_005271353 XM_011542340 XP_011540642 XM_011542341 XP_011540643 XM_011542342 XP_011540644 XM_011542343 XP_011540645 XM_011542344 XP_011540646 XM_011542345 XP_011540647 XM_011542346 XP_011540648 NM_003672 NP_003663 NM_033312 NP_201569 NM_033313 NP_201570
Function Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. {ECO:0000269|PubMed:11901424, ECO:0000269|PubMed:12134069, ECO:0000269|PubMed:17488717, ECO:0000269|PubMed:9367992}.
Subcellular Location Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the midzone of the mitotic spindle.
Top Pathways Cell cycle

Human Cdc14A full length protein - ab160093 from Abcam

Category Protein
Prices $402.00
Sizes 2 µg
Source Wheat germ
Species Human
ab160093 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Human Cdc14A protein fragment - ab160094 from Abcam

Category Protein
Prices $402.00
Sizes 10 µg
Source Wheat germ
Species Human
ab160094 on a 12.5% SDS-PAGE stained with Coomassie Blue.

Cdc14 / CDC14A Antibody Blocking Peptide - LS-E4832 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Cdc14 / CDC14A Antibody Blocking Peptide - LS-E23455 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Cdc14A Protein - H00008556-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

Cdc14A Recombinant Protein - H00008556-P02 from Novus Biologicals

Category Protein

CDC14A-Antibody-C-term-Blocking-Peptide - BP17213b from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CDC14A - H00008556-P02 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

CDC14A - H00008556-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

CDC14A - H00008556-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

CDC14A fusion protein - ag4556 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

CDC14A fusion protein - ag4969 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Dual specificity protein phosphatase CDC14A(CDC14A) - CSB-YP892158HU CSB-EP892158HU CSB-BP892158HU CSB-MP892158HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

Cdc14A Recombinant Protein Antigen - NBP1-84573PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Cdc14-Antibody-Blocking-peptide - BP8440a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

CDC14A Peptide, Human - M34GP02790H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Dual specificity protein phosphatase CDC14A (CDC14A), Recombinant Protein - MBS1414368 from MyBioSource

Category Protein
Prices $1,395.00, $1,395.00, $1,615.00, $1,615.00, $2,330.00, $2,330.00, $2,775.00, $2,775.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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