| Gene Symbol |
RNMT
|
| Entrez Gene |
8731
|
| Alt Symbol |
MET, RG7MT1, hCMT1c
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RNA (guanine-7-) methyltransferase
|
| Other Description |
hCMT1|hMet|hcm1p|mRNA (guanine-7-)methyltransferase|mRNA (guanine-N(7)-)-methyltransferase|mRNA cap guanine-N7 methyltransferase|mRNA cap methyltransferase
|
| Swissprots |
O94996 Q9UIJ9 D3DUJ5 B0YJ90 O43148
|
| Accessions |
ACA06068 EAX01505 EAX01506 EAX01507 O43148 AB007858 BAA23694 AB020966 BAA82447 AB022604 BAA74464 AB022605 BAA74463 AB022606 BAA74462 AF067791 AAC63269 AK292561 BAF85250 AK296370 BAH12334 AK303842 BAH14065 BC005290 AAH05290 BC017816 AAH17816 BC036798 AAH36798 BX647977 DA634865 XM_005258162 XP_005258219 XM_006722361 XP_006722424 XM_011525749 XP_011524051 XM_011525750 XP_011524052 XM_011525751 XP_011524053 XM_011525752 XP_011524054 XM_011525753 XP_011524055 NM_001308263 NP_001295192 NM_003799 NP_003790
|
| Function |
mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. Binds RNA containing 5'-terminal GpppC. {ECO:0000269|PubMed:10347220, ECO:0000269|PubMed:22099306, ECO:0000269|PubMed:9705270, ECO:0000269|PubMed:9790902}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11114884, ECO:0000269|PubMed:15767670}.
|
| Tissue Specificity |
Widely expressed. {ECO:0000269|PubMed:9705270, ECO:0000269|PubMed:9790902}.
|
| Top Pathways |
mRNA surveillance pathway
|
![Western Blot: RNMT Overexpression Lysate (Adult Normal) [NBL1-15467] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RNMT.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/7747_RNMT%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-15467-img0002.jpg)