Igf1
| Gene Symbol | Igf1 |
|---|---|
| Entrez Gene | 24482 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | insulin-like growth factor 1 |
| Other Description | IGF-I|insulin-like growth factor I|somatomedin |
| Swissprots | P08025 P08024 |
| Accessions | AAA41214 AAA41215 EDM17020 EDM17021 EDM17022 EDM17023 EDM17024 EDM17025 EDM17026 EDM17027 EDM17028 EDM17029 EDM17030 EDM17031 EDM17032 EDM17033 P08025 BC086374 AAH86374 CB751206 CB761687 D00698 BAA00604 FQ209824 FQ210560 FQ210688 FQ219829 FQ220385 FQ225388 FQ225437 FQ227442 FQ231951 FQ234943 FQ235332 M15480 AAA41385 M15481 AAA41387 M17335 AAA41386 M17592 AAA41388 M17593 AAA41389 M17594 AAA41390 M81184 X06043 CAA29436 X06107 CAA29480 X06108 CAA29481 XM_006241191 XP_006241253 XM_006241192 XP_006241254 XM_006241193 XP_006241255 XM_006241194 XP_006241256 NM_001082477 NP_001075946 NM_001082478 NP_001075947 NM_001082479 NP_001075948 NM_178866 NP_849197 |
| Function | The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted. |
| Top Pathways | Proteoglycans in cancer, Inflammatory mediator regulation of TRP channels, AMPK signaling pathway, Signaling pathways regulating pluripotency of stem cells, Ovarian steroidogenesis |
Search more
