CSNK1G2

Gene Symbol	CSNK1G2
Entrez Gene	1455
Alt Symbol	CK1g2
Species	Human
Gene Type	protein-coding
Description	casein kinase 1, gamma 2
Other Description	CKI-gamma 2|casein kinase 1 isoform gamma-2|casein kinase I isoform gamma-2
Swissprots	P78368 Q8WUB1 O00704 B5BU42
Accessions	AAC26983 EAW69426 EAW69427 EAW69428 EAW69429 EAW69430 EAW69431 P78368 AB451278 BAG70092 AB451410 BAG70224 AF001177 AAC00212 AY007134 AAG01997 BC018693 AAH18693 BC018699 AAH18699 BC020972 AAH20972 BT009922 AAP88924 CA423327 CR994929 DQ890695 ABM81621 DQ893880 ABM84806 U89896 AAB88627 XM_005259498 XP_005259555 XM_005259499 XP_005259556 XM_005259500 XP_005259557 XM_005259501 XP_005259558 XR_430129 NM_001319 NP_001310
Function	Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation. {ECO:0000269|PubMed:15077195, ECO:0000269|PubMed:15342122, ECO:0000269|PubMed:15917222, ECO:000
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:15077195}.
Tissue Specificity	Testis.
Top Pathways	Hedgehog signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human Casein Kinase 1 gamma 2 full length protein - ab104025 from Abcam Category Protein Prices $239.00, $352.00 Sizes 5 µg, 10 µg Source Baculovirus infected sf9 cells Species Human

Human Casein Kinase 1 gamma 2 full length protein - ab158217 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Casein Kinase 1 gamma 2 protein fragment - ab158218 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human Casein Kinase 1 gamma 2 protein fragment - ab185415 from Abcam Category Protein Prices $279.00 Sizes 10 µg Source E. coli Species Human

CSNK1G2 Antibody Blocking Peptide - LS-E8928 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CSNK1G2 Antibody Blocking Peptide - LS-E18639 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CSNK1G2 Antibody Blocking Peptide - LS-E18640 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Casein Kinase 1 gamma 2 Protein - H00001455-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Casein Kinase 1 gamma 2 Protein - H00001455-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Casein Kinase 1 gamma 2 Peptide - P2492 from Novus Biologicals Category Peptide Species Human

CSNK1G2-Antibody-C-term-Blocking-peptide - BP7405a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human CSNK1G2 His tag protein - orb84348 from Biorbyt Category Protein Prices $323.00, $434.00 Sizes 20 μg, 50 μg Source Insect Species Human

Human CSNK1G2 protein - orb180206 from Biorbyt Category Protein Prices $289.00, $621.00, $2,321.00, $3,281.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Species Human

CSNK1G2 - H00001455-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

CSNK1G2 - H00001455-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CSNK1G2 - H00001455-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CSNK1G2 - H00001455-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CSNK1G2 - H00001455-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CSNK1G2 - P5522 from Acris Antibodies Category Protein Prices $790.00 Sizes 5 µg Species Human

CSNK1G2 fusion protein - Ag2900 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human CSNK1G2, His tagged - CSNK1G2-905H from Creative Biomart Category Protein Source Baculovirus-Insect Cells Species Human

Recombinant Human CSNK1G2 - CSNK1G2-26811TH from Creative Biomart Category Protein Source Baculovirus infected sf9 cells

Recombinant Human CSNK1G2, GST-tagged - CSNK1G2-11631H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Casein Kinase 1, Gamma 2, His-tagged - CSNK1G2-680H from Creative Biomart Category Protein Source Insect cells .

Recombinant Human Casein Kinase 1, Gamma 2, GST-tagged - CSNK1G2-1008H from Creative Biomart Category Protein Species Human

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