Gene Symbol | mfsd2aa |
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Entrez Gene | 492810 |
Alt Symbol | NLS1-A, mfsd2a, zgc:101615 |
Species | Zebrafish |
Gene Type | protein-coding |
Description | major facilitator superfamily domain containing 2aa |
Other Description | major facilitator superfamily domain containing 2a|major facilitator superfamily domain-containing protein 2A-A|sodium-dependent LPC symporter 1-A|sodium-dependent lysophosphatidylcholine symporter 1-A |
Swissprots | Q5U3U7 |
Accessions | Q5U3U7 BC085388 AAH85388 XM_005156993 XP_005157050 XM_009307472 XP_009305747 NM_001007451 NP_001007452 |
Function | Sodium-dependent lysophosphatidylcholine (LPC) symporter, which plays an essential role for blood-brain barrier formation and function. Specifically expressed in endothelium of the blood-brain barrier of micro-vessels and transports LPC into the brain. Transport of LPC is essential because it constitutes the major mechanism by which docosahexaenoic acid (DHA), an omega- 3 fatty acid that is essential for normal brain growth and cognitive function, enters the brain. Transports LPC carrying long-chain fatty acids such LPC oleate and LPC palmitate with a minimum acyl chain length of 14 carbons. Does not transport docosahexaenoic acid in unesterified fatty acid. Specifically required for blood-brain barrier formation and function, probably by mediating lipid transport (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Anti-MFSD2A Antibody (C-Terminus) IHC-plus⢠- LS-B5348 from LifeSpan Bioscience
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Anti-MFSD2A Antibody (N-Terminus) - LS-C186690 from LifeSpan Bioscience
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Anti-MFSD2A antibody produced in rabbit - SAB3500576 from Sigma-Aldrich
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MFSD2A Antibody - 254373 from ABBIOTEC
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MFSD2A Antibody - 25208 from Signalway Antibody
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Anti-MFSD2A (C-terminal) polyclonal antibody - DPAB-L20751 from Creative Diagnostics
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MFSD2A, Polyclonal Antibody - MBS151344 from MyBioSource
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MFSD2A, Polyclonal Antibody - MBS243045 from MyBioSource
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mfsd2aa Antibody (OALA04913) - OALA04913 from Aviva Systems Biology
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MFSD2A, Polyclonal Antibody - MBS9405985 from MyBioSource
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MFSD2A-Antibody - ASC11224 from Abgent, a WuXi AppTec company
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Anti-MFSD2A Antibody (N-Terminus, HRP) - LS-C453354 from LifeSpan Bioscience
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Anti-MFSD2A Antibody (N-Terminus, FITC) - LS-C453355 from LifeSpan Bioscience
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Anti-MFSD2A Antibody (N-Terminus, Biotin) - LS-C453353 from LifeSpan Bioscience
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Anti-MFSD2A Antibody - LS-C406569 from LifeSpan Bioscience
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Anti-MFSD2A Antibody - LS-C403326 from LifeSpan Bioscience
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NLS1A Antibody - CSB-PA719454XA01DIL from Cusabio
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