Gene Symbol |
ACS1
|
Entrez Gene |
851245
|
Alt Symbol |
FUN44
|
Species |
Yeast
|
Gene Type |
protein-coding
|
Description |
acetate--CoA ligase 1
|
Other Description |
-
|
Swissprots |
D6VPG4 Q66RJ0 Q01574
|
Accessions |
DAA06934 Q01574 NM_001178197 NP_009347
|
Function |
Catalyzes the production of acetyl-CoA. Provides the acetyl-CoA source for histone acetylation in the nucleus. "Aerobic" isozyme of acetyl-coenzyme A synthetase, which supports growth on nonfermentable carbon sources such as glycerol and ethanol. May be required for assimilation of ethanol and acetate. {ECO:0000269|PubMed:16857587, ECO:0000269|PubMed:8910545}.
|
Subcellular Location |
Microsome {ECO:0000305}. Cytoplasm. Mitochondrion. Nucleus.
|
Top Pathways |
Glycolysis / Gluconeogenesis, Methane metabolism, Pyruvate metabolism, Carbon metabolism, Propanoate metabolism
|