LTBP4
| Gene Symbol | LTBP4 |
|---|---|
| Entrez Gene | 8425 |
| Alt Symbol | ARCL1C, LTBP-4, LTBP4L, LTBP4S |
| Species | Human |
| Gene Type | protein-coding |
| Description | latent transforming growth factor beta binding protein 4 |
| Other Description | latent transforming growth factor-beta binding protein 4L|latent-transforming growth factor beta-binding protein 4 |
| Swissprots | O75412 Q8N2S1 O00508 O75413 |
| Accessions | CBX47603 CBX47604 CBX47605 EAW56982 EAW56983 EAW56984 EAW56985 Q8N2S1 AF051344 AAC39879 AF051345 AAC39880 AF054501 AAC39881 AF054502 AAC39882 AK074499 BAC11024 AK128191 BAG54648 AK303613 BAH13998 AK304612 BAH14224 AK309484 BQ001109 Y13622 CAA73944 XM_011527376 XP_011525678 XM_011527377 XP_011525679 XM_011527378 XP_011525680 XM_011527379 XP_011525681 XM_011527380 XP_011525682 XM_011527381 XP_011525683 XM_011527382 XP_011525684 XM_011527383 XP_011525685 XM_011527384 XP_011525686 XM_011527385 XP_011525687 XM_011527386 XP_011525688 XM_011527387 XP_011525689 NM_001042544 NP_001036009 NM_001042545 NP_001036010 NM_003573 NP_003564 |
| Function | May be involved in the assembly, secretion and targeting of TGFB1 to sites at which it is stored and/or activated. May play critical roles in controlling and directing the activity of TGFB1. May have a structural role in the extra cellular matrix (ECM) (By similarity). {ECO:0000250}. |
| Subcellular Location | Secreted, extracellular space, extracellular matrix {ECO:0000269|PubMed:16157329, ECO:0000269|PubMed:9660815}. |
| Tissue Specificity | Highly expressed in heart, skeletal muscle, pancreas, uterus, and small intestine. Weakly expressed in placenta and lung. {ECO:0000269|PubMed:9271198, ECO:0000269|PubMed:9660815}. |
LTBP-4 CRISPR/Cas9 KO Plasmid (h) - sc-405419 from Santa Cruz Biotechnology
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LTBP-4 HDR Plasmid (h) - sc-405419-HDR from Santa Cruz Biotechnology
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LTBP-4 Double Nickase Plasmid (h) - sc-405419-NIC from Santa Cruz Biotechnology
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LTBP-4 Double Nickase Plasmid (h2) - sc-405419-NIC-2 from Santa Cruz Biotechnology
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LTBP-4 CRISPR Activation Plasmid (h) - sc-405419-ACT from Santa Cruz Biotechnology
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LTBP-4 CRISPR Activation Plasmid (h2) - sc-405419-ACT-2 from Santa Cruz Biotechnology
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LTBP-4 Lentiviral Activation Particles (h) - sc-405419-LAC from Santa Cruz Biotechnology
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LTBP-4 Lentiviral Activation Particles (h2) - sc-405419-LAC-2 from Santa Cruz Biotechnology
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LTBP-4 siRNA (h) - sc-45861 from Santa Cruz Biotechnology
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LTBP-4 shRNA Plasmid (h) - sc-45861-SH from Santa Cruz Biotechnology
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LTBP-4 shRNA (h) Lentiviral Particles - sc-45861-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU095771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12818 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12818 from Sigma-Aldrich
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LTBP4 siRNA (Human) - CRH5519 from Cohesion Biosciences
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Latent TGF-beta bp4 RNAi - H00008425-R03 from Novus Biologicals
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shRNA set against Human LTBP4 (NM_003573.2) - SHH335499 from Creative biogene
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shRNA set against Human LTBP4(NM_001042544.1) - SHH166115 from Creative biogene
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shRNA set against Human LTBP4(NM_003573.2) - SHH166123 from Creative biogene
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shRNA set against Human LTBP4(NM_001042544.1) - SHH166141 from Creative biogene
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shRNA set against Human LTBP4(NM_001042545.1) - SHH166187 from Creative biogene
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Human LTBP4 siRNA - orb266021 from Biorbyt
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LTBP4 shRNA Plasmid (Human) - CHH5519 from Cohesion Biosciences
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LTBP4 miRNA 3'UTR clone - MiUTR1H-05951 from Creative biogene
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LTBP4 miRNA 3'UTR clone - MiUTR1H-05952 from Creative biogene
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