ACSL3

Gene Symbol ACSL3
Entrez Gene 2181
Alt Symbol ACS3, FACL3, PRO2194
Species Human
Gene Type protein-coding
Description acyl-CoA synthetase long-chain family member 3
Other Description LACS 3|fatty-acid-Coenzyme A ligase, long-chain 3|lignoceroyl-CoA synthase|long-chain acyl-CoA synthetase 3|long-chain-fatty-acid--CoA ligase 3
Swissprots Q8IUM9 Q60I92 O95573
Accessions BAB72139 CBF65064 CBU89935 EAW70807 EAW70808 EAW70809 O95573 AB061712 BAB72074 AF116690 AAF71110 AI378485 AK001471 BAG50918 AK023191 BAG51167 AK314621 BAG37187 BC012066 BC032144 AAH32144 BC041692 AAH41692 BF679686 BG772246 BM971377 BQ435549 BX472576 D89053 BAA37142 N44998 XR_922889 NM_004457 NP_004448 NM_203372 NP_976251
Function Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins). {ECO:0000250, ECO:0000269|PubMed:18003621}.
Subcellular Location Mitochondrion outer membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Peroxisome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Microsome membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type III membrane protein {ECO:0000250}.
Top Pathways Adipocytokine signaling pathway, PPAR signaling pathway, Peroxisome, Fatty acid biosynthesis, Fatty acid degradation

ACSL3 (F-9) - sc-271246 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ACSL3 (F-9): sc-271246. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

ACSL3 (H-9) - sc-166374 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
ACSL3 (H-9): sc-166374. Western blot analysis of ACSL3 expression in TE671 whole cell lysate.

ACSL3 (H-96) - sc-134497 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

ACSL3 (K-13) - sc-47991 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACSL3 (K-13): sc-47991. Western blot analysis of ACSL3 expression in TE671 whole cell lysate.

ACSL3 (N-17) - sc-47994 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

ACSL3 (N-12) - sc-47993 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ACSL3 (N-12): sc-47993. Western blot analysis of ACSL3 expression in TE671 whole cell lysate.

Anti-ACSL3 antibody - ab151959 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ACSL3 antibody (ab151959) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-ACSL3 antibody - ab80675 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-ACSL3 antibody (ab80675) at 1 µg/ml + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-ACSL3 antibody - ab167333 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-ACSL3 antibody (ab167333) at 1 µg/mlLane 1 : ACSL3 transfected 293T cell lysateLane 2 : Non transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG HRP at 1/2500 dilution

Anti-ACSL3 antibody - ab78229 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of ACSL3 expression in Formalin-Fixed Paraffin Embedded human Skeletal muscle using 20 µg/ml ab78229

Anti-ACSL3 antibody - ab129788 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-ACSL3 antibody (ab129788) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-ACSL3 antibody - Aminoterminal end - ab55940 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (aa528-556, AP) - LS-C221341 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (aa528-556, APC) - LS-C221342 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (aa528-556, FITC) - LS-C221343 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (aa528-556, Biotin) - LS-C221344 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (aa528-556, Azide-free, HRP) - LS-C221345 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (aa528-556, PE) - LS-C221346 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (N-Terminus, APC) - LS-C224798 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (N-Terminus, AP) - LS-C224797 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (N-Terminus, Biotin) - LS-C224799 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody (aa74-123) - LS-C80894 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ACSL3 Antibody (N-Terminus, Azide-free, HRP) - LS-C224801 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACSL3 Antibody - LS-C306067 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-ACSL3 Antibody (N-Terminus, PE) - LS-C224802 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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