| Gene Symbol |
SYNPO2
|
| Entrez Gene |
171024
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
synaptopodin 2
|
| Other Description |
genethonin-2|myopodin|synaptopodin-2
|
| Swissprots |
B2RWP6 B2Y8J9 S5XAM4 Q9UK89 Q9UMS6
|
| Accessions |
Q9UMS6 AA043349 AF177291 AAD55264 AJ010482 CAB51856 AK000774 AK296962 BAG59506 AK304121 BAG65020 AK307711 AL832031 AL832363 AL833294 AL833547 AM392848 CAL37726 AM393854 CAL38729 AV734727 BC136256 AAI36257 BC150629 AAI50630 BX647849 BX648090 CB998857 CR936673 EU481975 ACC93875 FN422000 CAZ66141 KF147165 AGS94404 XM_011531703 XP_011530005 NM_001128933 NP_001122405 NM_001128934 NP_001122406 NM_001286754 NP_001273683 NM_001286755 NP_001273684 NM_133477 NP_597734
|
| Function |
Has an actin-binding and actin-bundling activity. {ECO:0000250}.
|
| Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm in a differentiation-dependent and stress-induced fashion. Localizes to the Z-disk in mature striated muscle. The nuclear export is XPO1-dependent (By similarity). Localized in a fiber- like pattern. partly overlapping with filamentous actin. {ECO:0000250, ECO:0000269|PubMed:18371299}.
|
| Tissue Specificity |
Skeletal muscle specific. {ECO:0000269|PubMed:11297942}.
|