Gene Symbol | LEMD2 |
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Entrez Gene | 221496 |
Alt Symbol | NET25, dJ482C21.1 |
Species | Human |
Gene Type | protein-coding |
Description | LEM domain containing 2 |
Other Description | LEM domain-containing protein 2|hLEM2 |
Swissprots | Q5T972 B4DVH5 E7EVT2 Q5T974 Q8NC56 |
Accessions | CAF86155 EAX03750 EAX03751 Q8NC56 AK024858 AK026077 AK074959 BAC11316 AK127084 AK301083 BAG62687 AK309888 BC039864 BC051803 AAH51803 BM978238 DC340017 XR_926111 NM_001143944 NP_001137416 NM_181336 NP_851853 |
Function | Involved in nuclear structure organization. {ECO:0000269|PubMed:16339967}. |
Subcellular Location | Nucleus inner membrane {ECO:0000269|PubMed:16339967}; Multi-pass membrane protein {ECO:0000269|PubMed:16339967}. Note=Lamina-associated protein residing in the inner nuclear membrane (INM). Localized exclusively to the nuclear envelope, giving rise to a typical rim- like staining of the nuclear periphery. |
Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:16339967}. |
LEMD2 CRISPR/Cas9 KO Plasmid (h) - sc-408348 from Santa Cruz Biotechnology
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LEMD2 HDR Plasmid (h) - sc-408348-HDR from Santa Cruz Biotechnology
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LEMD2 Double Nickase Plasmid (h) - sc-408348-NIC from Santa Cruz Biotechnology
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LEMD2 Double Nickase Plasmid (h2) - sc-408348-NIC-2 from Santa Cruz Biotechnology
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LEMD2 CRISPR Activation Plasmid (h) - sc-408348-ACT from Santa Cruz Biotechnology
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LEMD2 CRISPR Activation Plasmid (h2) - sc-408348-ACT-2 from Santa Cruz Biotechnology
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LEMD2 Lentiviral Activation Particles (h) - sc-408348-LAC from Santa Cruz Biotechnology
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LEMD2 Lentiviral Activation Particles (h2) - sc-408348-LAC-2 from Santa Cruz Biotechnology
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LEMD2 siRNA (h) - sc-95337 from Santa Cruz Biotechnology
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LEMD2 shRNA Plasmid (h) - sc-95337-SH from Santa Cruz Biotechnology
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LEMD2 shRNA (h) Lentiviral Particles - sc-95337-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU023351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11641 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11641 from Sigma-Aldrich
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LEMD2 siRNA (Human) - CRJ6524 from Cohesion Biosciences
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shRNA set against Human LEMD2 (NM_181336.3) - SHH329519 from Creative biogene
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Human LEMD2 siRNA - orb277025 from Biorbyt
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LEMD2 shRNA Plasmid (Human) - CHJ6524 from Cohesion Biosciences
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LEMD2 miRNA 3'UTR clone - MiUTR3H-15300 from Creative biogene
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LEMD2 miRNA 3'UTR clone - MiUTR3H-15301 from Creative biogene
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