Gene Symbol | Adcy6 |
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Entrez Gene | 11512 |
Alt Symbol | AC6, mKIAA0422 |
Species | Mouse |
Gene Type | protein-coding |
Description | adenylate cyclase 6 |
Other Description | ATP pyrophosphate-lyase 6|adenylate cyclase type 6|adenylate cyclase type VI|adenylyl cyclase 6|ca(2+)-inhibitable adenylyl cyclase |
Swissprots | Q01341 |
Accessions | EDL04180 Q01341 AK078078 AK122279 BAC65561 AK147516 BC145101 BC156960 AAI56961 BU611374 M93422 AAA37174 M96653 AAA37182 XM_006520303 XP_006520366 XM_006520306 XP_006520369 XM_006520307 XP_006520370 XM_006520314 XP_006520377 XM_006520315 XP_006520378 XR_383971 XR_383972 XR_875221 NM_007405 NP_031431 |
Function | Membrane-bound, calcium-inhibitable adenylyl cyclase. |
Subcellular Location | Membrane {ECO:0000269|PubMed:21670265}; Multi-pass membrane protein {ECO:0000269|PubMed:21670265}. Cell projection, cilium {ECO:0000269|PubMed:21670265}. |
Tissue Specificity | Most abundant in heart but weakly detectable in brain, intestine, lung and spleen. |
Top Pathways | Inflammatory mediator regulation of TRP channels, Thyroid hormone synthesis, Adrenergic signaling in cardiomyocytes, HTLV-I infection, cAMP signaling pathway |
A cyclase VI CRISPR/Cas9 KO Plasmid (m) - sc-418996 from Santa Cruz Biotechnology
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A cyclase VI HDR Plasmid (m) - sc-418996-HDR from Santa Cruz Biotechnology
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A cyclase VI Double Nickase Plasmid (m) - sc-418996-NIC from Santa Cruz Biotechnology
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A cyclase VI Double Nickase Plasmid (m2) - sc-418996-NIC-2 from Santa Cruz Biotechnology
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A cyclase VI CRISPR Activation Plasmid (m) - sc-418996-ACT from Santa Cruz Biotechnology
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A cyclase VI CRISPR Activation Plasmid (m2) - sc-418996-ACT-2 from Santa Cruz Biotechnology
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A cyclase VI Lentiviral Activation Particles (m) - sc-418996-LAC from Santa Cruz Biotechnology
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A cyclase VI Lentiviral Activation Particles (m2) - sc-418996-LAC-2 from Santa Cruz Biotechnology
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A cyclase VI siRNA (m) - sc-40322 from Santa Cruz Biotechnology
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A cyclase VI shRNA Plasmid (m) - sc-40322-SH from Santa Cruz Biotechnology
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A cyclase VI shRNA (m) Lentiviral Particles - sc-40322-V from Santa Cruz Biotechnology
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A cyclase V/VI siRNA (m) - sc-43588 from Santa Cruz Biotechnology
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A cyclase V/VI shRNA Plasmid (m) - sc-43588-SH from Santa Cruz Biotechnology
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A cyclase V/VI shRNA (m) Lentiviral Particles - sc-43588-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU064101 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26319 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26319 from Sigma-Aldrich
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ADCY6 siRNA (Mouse) - CRM0067 from Cohesion Biosciences
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ADCY6 - MBS8210753 from MyBioSource
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A cyclase VI CRISPR/Cas9 KO Plasmid (m2) - sc-418996-KO-2 from Santa Cruz Biotechnology
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A cyclase VI HDR Plasmid (m2) - sc-418996-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Mouse ADCY6 (NM_007405.2) - SHH232234 from Creative biogene
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shRNA set against Mouse Adcy6(NM_007405.2) - SHG041297 from Creative biogene
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Mouse ADCY6 siRNA - orb279543 from Biorbyt
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ADCY6 shRNA Plasmid (Mouse) - CHM0067 from Cohesion Biosciences
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