PTPN11

Gene Symbol	PTPN11
Entrez Gene	5781
Alt Symbol	BPTP3, CFC, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
Species	Human
Gene Type	protein-coding
Description	protein tyrosine phosphatase, non-receptor type 11
Other Description	PTP-2C|protein-tyrosine phosphatase 1D|protein-tyrosine phosphatase 2C|tyrosine-protein phosphatase non-receptor type 11
Swissprots	A8K1D9 Q96HD7 Q06124
Accessions	EAW98011 EAW98012 Q06124 AK289854 BAF82543 AK312147 BAG35082 AU123593 BC007869 BC008692 AAH08692 BC025181 AAH25181 BC030949 AAH30949 BF515187 BT007106 AAP35770 BX537632 CN258646 D13540 BAA02740 EU779706 ACE60554 EU779707 ACE60555 EU779708 ACE60556 L03535 AAA36611 L07527 AAA17022 L08807 S39383 S78088 AAB21148 U79291 X70766 CAA50045 XM_006719526 XP_006719589 XM_006719527 XP_006719590 XM_011538613 XP_011536915 NM_002834 NP_002825 NM_080601 NP_542168
Function	Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity. {ECO:0000269|PubMed:10655584, ECO:0000269|PubMed:18559669, ECO:0000269|PubMed:18829466}.
Subcellular Location	Cytoplasm.
Tissue Specificity	Widely expressed, with highest levels in heart, brain, and skeletal muscle. {ECO:0000269|PubMed:1280823, ECO:0000269|PubMed:7681589, ECO:0000269|PubMed:8216283}.
Top Pathways	Proteoglycans in cancer, Jak-STAT signaling pathway, Herpes simplex infection, Neurotrophin signaling pathway, Renal cell carcinoma

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PTPN11 Gene cDNA Clone - orb144930 from Biorbyt Prices $255.00 Sizes 10 μg Species Human

Human-PTPN11-cDNA-Clone - DC05449 from Abgent, a WuXi AppTec company Prices $621.00 Sizes 10 µg Species Human Accession NM_002834

Human PTPN11 cDNA clone(NM_002834.3) - CDFH015514 from Creative Biomart Species Human Accession NM_002834.3

Human PTPN11 ORF Clone(NM_002834.3) - CDCR284182 from Creative Biomart Species Human Accession NM_002834.3

Human PTPN11 ORF Clone(NM_002834.3) - CDCR284183 from Creative Biomart Species Human Accession NM_002834.3

Human PTPN11 ORF Clone(NM_002834.3) - CDCL172960 from Creative Biomart Species Human Accession NM_002834.3

Human SHP2 / PTPN11 Gene ORF cDNA clone in cloning vector - HG12318-G from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG12318-NF from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, C-HA tag - HG12318-CY from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12318-NM from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12318-CF from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, N-HA tag - HG12318-NY from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, N-His tag - HG12318-NH from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG12318-CM from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG12318-ACR from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid - HG12318-UT from Sino Biological Species Human

Human PTPN11 Gene cDNA Clone (full-length ORF Clone), expression ready, N-OFPSpark tag - HG12318-ANR from Sino Biological Species Human Accession BC008692

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, C-His tag - HG12318-CH from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG12318-ANG from Sino Biological Species Human

Human SHP2 / PTPN11 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG12318-ACG from Sino Biological Species Human

NS1, cDNA Clone - MBS1491643 from MyBioSource Prices $610.00 Sizes 10ug plasmid + 200ul glycerol stock

human PTPN11 ORF clone (NM_002834.3) - CDCH069610 from Creative biogene Species Human

Human PTPN11 ORF Clone (BC008692) - CDCS411000 from Creative biogene Species Human Accession Q06124

Human PTPN11 ORF Clone (BC025181) - CDCS411001 from Creative biogene Species Human Accession Q06124

Human PTPN11 ORF clone (BC008692) - CDCB160122 from Creative biogene Species Human

Search more