Sema4d

Gene Symbol Sema4d
Entrez Gene 20354
Alt Symbol CD100, Semacl2, Semaj, Semcl2, coll-4
Species Mouse
Gene Type protein-coding
Description sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
Other Description M-sema G|sema J|semaphorin H|semaphorin-4D|semaphorin-C-like 2|semaphorin-J
Swissprots Q6GTM9 O09126
Accessions EDL41105 EDL41106 EDL41107 O09126 AK088653 BAC40480 AK132688 BAE21302 AK150911 BC027681 BC049780 AAH49780 BE692125 U69535 AAC52964 XM_006516883 XP_006516946 XM_006516884 XP_006516947 XM_006516885 XP_006516948 XM_006516886 XP_006516949 XM_006516887 XP_006516950 XM_006516888 XP_006516951 XM_006516891 XP_006516954 XM_006516892 XP_006516955 NM_001281880 NP_001268809 NM_013660 NP_038688
Function Cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. Promotes reorganization of the actin cytoskeleton and plays a role in axonal growth cone guidance in the developing central nervous system. Regulates dendrite and axon branching and morphogenesis. Promotes the migration of cerebellar granule cells and of endothelial cells. Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro). Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade. Interaction with PLXNB1 mediates activation of RHOA (By similarity). {ECO:0000250}.
Subcellular Location Cell membrane; Single-pass type I membrane protein.
Tissue Specificity Strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous tissues.
Top Pathways Axon guidance

Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera, CF - 5235-S4-050 from R&D Systems

Category Protein
Source Mouse myeloma cell line, NS0-derived

Recombinant Mouse Sema4d, His tagged - Sema4d-4066M from Creative Biomart

Category Protein
Source Human Cells
Species Mouse

Recombinant Mouse Sema4d, Fc Chimera - Sema4d-677M from Creative Biomart

Category Protein
Source NSO Cells
Species Mouse

Mouse Semaphorin 4D / SEMA4D / CD100 Protein (His Tag) - 50642-M08H-50 from Sino Biological

Category Protein
Prices $178.00, $298.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Mouse

Recombinant Semaphorin 4D (SEMA4D) - RPB430Mu01 from Cloud-clone

Category Protein
Source E.coli
Species Mouse

Recombinant Mouse Semaphorin-4D(Sema4d) - CSB-YP020990MO CSB-EP020990MO CSB-BP020990MO CSB-MP020990MO from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Mouse

Recombinant Mouse Semaphorin 4D/CD100 Fc Chimera Protein, CF - 5235-S4 from R&D Systems

Category Protein
Prices $325.00
Sizes 50 µg
Source Mouse myeloma cell line, NS0-derived Mouse Semaphorin 4D (Phe24-Met711) Accession # NP_038688 IEGRMDP Mouse IgG 2A (Glu98-Lys330) N-terminus C-terminus
Species Mouse

Recombinant Mouse Semaphorin 4D / SEMA4D / CD100 Protein (His tag) - PKSM040568 from Elabscience

Category Protein
Source Human Cell
Species Mouse

SEMA4D Recombinant Protein (OPCD06908) - OPCD06908 from Aviva Systems Biology

Category Protein
Source E.coli
Species Mouse

Mouse Semaphorin 4D / SEMA4D / CD100 Protein (His Tag) - 50642-M08H from ABclonal

Category Protein
Prices $178.00, $298.00
Sizes 50 µg, 100 µg
Source Human Cells
Species Mouse

Semaphorin 4D Recombinant Protein - 92-410 from ProSci

Category Protein
Prices $315.00
Sizes 50 µg
Source Human Cells
Species Mouse

SEMA4D, Recombinant Protein - MBS8249751 from MyBioSource

Category Protein
Prices $190.00, $410.00, $1,790.00
Sizes 10 µg, 50 µg, 500 µg
Source Human cells
Species Mouse

Semaphorin 4D / SEMA4D / CD100, Recombinant Protein - MBS2546870 from MyBioSource

Category Protein
Prices $475.00, $775.00
Sizes 50 µg, 100 µg
Source Human Cells

Semaphorin-4D (Sema4d), Recombinant Protein - MBS1243731 from MyBioSource

Category Protein
Prices $1,515.00, $1,515.00, $1,745.00, $1,745.00, $2,600.00, $2,600.00, $3,040.00, $3,040.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Mouse

Recombinant Mouse Semaphorin 4D,SEMA4D (C-Fc) - AP76071 from Signalway Antibody

Category Protein
Prices $259.00, $479.00, $1,599.00, $2,369.00
Sizes 10 µg, 50 µg, 500 µg, 1 mg
Source Human Cells
Species Mouse

Mouse SEMA4D protein - orb392441 from Biorbyt

Category Protein
Species Mouse

Mouse CD100 protein (C-Fc) - orb311999 from Biorbyt

Category Protein
Species Mouse
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