Gene Symbol | PSMC2 |
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Entrez Gene | 5701 |
Alt Symbol | MSS1, Nbla10058, S7 |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) 26S subunit, ATPase, 2 |
Other Description | 26S protease regulatory subunit 7|26S proteasome AAA-ATPase subunit RPT1|mammalian suppressor of sgv-1 of yeast|protease 26S subunit 7|proteasome 26S subunit ATPase 2|proteasome 26S subunit, ATPase, 2|putative protein product of Nbla10058 |
Swissprots | P35998 Q9UDI3 B7Z5E2 Q3LIA5 A4D0Q1 |
Accessions | AAS07429 EAL24412 EAW83331 EAW83332 EAW83333 P35998 AB075520 BAE45763 AK298529 BAH12807 AK298821 BAH12878 AK312648 BC002589 AAH02589 BE269755 BM754312 BU675889 D11094 BAA01868 EU446703 ABZ92232 XM_005250505 XP_005250562 NM_001204453 NP_001191382 NM_002803 NP_002794 |
Function | The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. In case of HIV-1 infection, positive modulator of Tat-mediated transactivation. {ECO:0000269|PubMed:9295362}. |
Subcellular Location | Cytoplasm. Nucleus. Cytoplasm, P-body {ECO:0000250}. Note=Colocalizes with TRIM5 in the cytoplasmic bodies. {ECO:0000250}. |
Top Pathways | Proteasome, Epstein-Barr virus infection |
PSMC2 (D5T1T) Rabbit mAb - 14395 from Cell Signaling Technology
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PSMC2 (C-1) - sc-166972 from Santa Cruz Biotechnology
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PSMC2 (H-102) - sc-98691 from Santa Cruz Biotechnology
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PSMC2 (L-17) - sc-74874 from Santa Cruz Biotechnology
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PSMC2 (C-15) - sc-74872 from Santa Cruz Biotechnology
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PSMC2 (O-22) - sc-133932 from Santa Cruz Biotechnology
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Anti-Proteasome 19S S7 antibody - ab3322 from Abcam
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Anti-Proteasome 19S S7 antibody - ab49058 from Abcam
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Anti-Proteasome 19S S7 antibody - ab91046 from Abcam
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Anti-Proteasome 19S S7 antibody - ab123307 from Abcam
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Anti-Proteasome 19S S7 antibody [15] - ab83081 from Abcam
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Anti-PSMC2 / RPT1 Antibody - LS-C86222 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody - LS-C137484 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-30, AP) - LS-C267296 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-30, APC) - LS-C267299 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-30, Biotin) - LS-C267300 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (N-Terminus) - LS-C31036 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-30, FITC) - LS-C267301 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-30, PE) - LS-C267303 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-30, Azide-free, HRP) - LS-C267302 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (N-Terminus) - LS-C109885 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa150-200) - LS-C290473 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-30) - LS-C162237 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa483-433) - LS-C290472 from LifeSpan Bioscience
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Anti-PSMC2 / RPT1 Antibody (aa1-434, Azide-free) - LS-C328337 from LifeSpan Bioscience
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