Gene Symbol |
ARL1
|
Entrez Gene |
400
|
Alt Symbol |
ARFL1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
ADP-ribosylation factor-like 1
|
Other Description |
ADP-ribosylation factor-like protein 1
|
Swissprots |
P80417 P40616 Q53XB1 B4DWW1
|
Accessions |
EAW97657 EAW97658 EAW97659 EAW97660 P40616 AF493887 AAM12601 AI802608 AK001489 AK299062 BAG61128 AK301701 BAG63173 AK302911 BAG64079 AK311793 BAG34736 AL701988 AM393841 CAL38716 BC007000 AAH07000 BT007260 AAP35924 BX537387 CAD97629 CD686919 CK822904 DC343685 DQ893048 ABM83974 DQ896295 ABM87294 L28997 AAC37567 NM_001177 NP_001168 NM_001301068 NP_001287997
|
Function |
GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus. {ECO:0000269|PubMed:9624189}.
|
Subcellular Location |
Golgi apparatus membrane {ECO:0000269|PubMed:11303027}; Peripheral membrane protein {ECO:0000269|PubMed:11303027}; Cytoplasmic side {ECO:0000269|PubMed:11303027}.
|
Tissue Specificity |
Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney. Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9624189}.
|