Gene Symbol | C3 |
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Entrez Gene | 718 |
Alt Symbol | AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p |
Species | Human |
Gene Type | protein-coding |
Description | complement component 3 |
Other Description | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1|C3a anaphylatoxin|acylation-stimulating protein cleavage product|complement C3|complement component C3|complement component C3a|complement component C3b|epididymis secretory sperm binding protein Li 62p|prepro-C3 |
Swissprots | A7E236 P01024 |
Accessions | AAA35722 AAR89906 CAI46844 EAW69070 EAW69071 P01024 AA025232 AI758500 AK094728 AK304071 BAG64978 BC022897 BC063852 BC150179 AAI50180 BC150200 AAI50201 BC150299 BP201387 BP349355 EU794602 ACJ13656 K02765 AAA85332 KC493376 KC493377 M55658 NM_000064 NP_000055 |
Function | C3-beta-c: Acts as a chemoattractant for neutrophils in chronic inflammation. {ECO:0000250}. |
Subcellular Location | Secreted. |
Tissue Specificity | Plasma. The acylation stimulating protein (ASP) is expressed in adipocytes and released into the plasma during both the fasting and postprandial periods. {ECO:0000269|PubMed:15833747, ECO:0000269|PubMed:9555951}. |
Top Pathways | Phagosome, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection, Complement and coagulation cascades, Pertussis |
Human C3 full length protein - ab167802 from Abcam
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Human C3 protein fragment - ab157985 from Abcam
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Human C3 protein fragment - ab176059 from Abcam
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Human C3c full length protein - ab96038 from Abcam
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Complement C3 Antibody Blocking Peptide - LS-E27967 from LifeSpan Bioscience
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Complement C3 Antibody Blocking Peptide - LS-E27968 from LifeSpan Bioscience
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Recombinant Human Complement C3 Protein - H00000718-Q01 from Novus Biologicals
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Complement C3 Protein - P4945 from Novus Biologicals
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C3-Antibody-C-term-Blocking-peptide - BP13691b from Abgent, a WuXi AppTec company
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C3-Peptide-P16 - SP2896b from Abgent, a WuXi AppTec company
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C3-Peptide-P16 - SP2896a from Abgent, a WuXi AppTec company
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Recombinant Human Complement Component C3a, CF - 3677-C3-025 from R&D Systems
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Recombinant human Complement C3 (OPCA00876) - OPCA00876 from Aviva Systems Biology
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C3 Protein (OPSA11762) - OPSA11762 from Aviva Systems Biology
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Human C3 protein - orb245466 from Biorbyt
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Complement C3 protein - 32R-AC021 from Fitzgerald
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Complement C3 protein - 32C-CP1036U from Fitzgerald
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Complement C3 protein - 30-1086 from Fitzgerald
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Complement C3a protein - 32C-CP1039 from Fitzgerald
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Human C3a Protein - abx066057 from Abbexa
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Human Complement C3 Protein (Active) - abx060231 from Abbexa
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Human Complement C3 Protein (Active) - abx060106 from Abbexa
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Human Complement Component 3 Protein - abx066051 from Abbexa
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Human Complement Component 3 Protein - abx066053 from Abbexa
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Complement C3 Peptide - AC21-2732-P from Abcore
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