| Gene Symbol |
TRDMT1
|
| Entrez Gene |
1787
|
| Alt Symbol |
DMNT2, DNMT2, MHSAIIP, PUMET, RNMT1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tRNA aspartic acid methyltransferase 1
|
| Other Description |
DNA (cytosine-5)-methyltransferase-like protein 2|DNA MTase homolog HsaIIP|DNA methyltransferase-2|tRNA (cytosine(38)-C(5))-methyltransferase|tRNA (cytosine-5-)-methyltransferase
|
| Swissprots |
Q86WW6 O43669 B0YJ08 B0YJ07 O14717 B0YJ02 B0YJ03
|
| Accessions |
ACA05981 ACA05982 ACA05983 ACA05984 ACA05986 ACA05987 EAW86217 EAW86218 EAW86219 O14717 AF012128 AAC51939 AF045888 AAC39764 AF329940 AAK68034 AF329941 AAK68035 AF329942 AAK68036 AF329943 AAK68037 AF329944 AAK68033 AJ223333 CAA11272 AK021659 AK123512 AK291417 BAF84106 AK294100 BAH11673 AK299027 BAG61104 AK303428 BAH13958 BC047733 AAH47733 BU620523 BX537961 CAD97925 CR450316 CAG29312 DC411638 XM_005252372 XP_005252429 XM_005252374 XP_005252431 XM_005252375 XP_005252432 XM_005252376 XP_005252433 XM_005252378 XP_005252435 XM_006717388 XP_006717451 XM_011519343 XP_011517645 XM_011519344 XP_011517646 XM_011519345 XP_011517647 XM_011519346 XP_011517648 XM_011519347 XP_011517649 NM_004412 NP_004403 NM_176081 NM_176083 NM_176084 NM_176085 NM_176086
|
| Function |
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp). {ECO:0000269|PubMed:16424344}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes.
|
![Western Blot: Dnmt2 Overexpression Lysate (Adult Normal) [NBL1-17263] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Dnmt2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8883_Dnmt2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17263-img0002.jpg)