Gene Symbol | WDR12 |
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Entrez Gene | 55759 |
Alt Symbol | YTM1 |
Species | Human |
Gene Type | protein-coding |
Description | WD repeat domain 12 |
Other Description | WD repeat-containing protein 12|ribosome biogenesis protein WDR12 |
Swissprots | B3KPA9 Q9NV80 Q9NYI8 Q96HU0 Q9GZL7 |
Accessions | AAY24287 EAW70318 EAW70319 Q9GZL7 AF242546 AAF60355 AK001743 BAA91875 AK022781 BAB14242 AK022782 BAB14243 AK056092 BAG51621 AK299489 BAG61449 BC008082 AAH08082 BU633688 DQ892874 ABM83800 DQ896123 ABM87122 EF011617 ABK41107 XM_011511469 XP_011509771 NM_018256 NP_060726 |
Function | Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. {ECO:0000255|HAMAP-Rule:MF_03029, ECO:0000269|PubMed:16043514, ECO:0000269|PubMed:17353269}. |
Subcellular Location | Nucleus, nucleolus. Nucleus, nucleoplasm. |
WDR12 CRISPR/Cas9 KO Plasmid (h) - sc-418080 from Santa Cruz Biotechnology
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WDR12 HDR Plasmid (h) - sc-418080-HDR from Santa Cruz Biotechnology
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WDR12 Double Nickase Plasmid (h) - sc-418080-NIC from Santa Cruz Biotechnology
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WDR12 Double Nickase Plasmid (h2) - sc-418080-NIC-2 from Santa Cruz Biotechnology
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WDR12 CRISPR Activation Plasmid (h) - sc-418080-ACT from Santa Cruz Biotechnology
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WDR12 CRISPR Activation Plasmid (h2) - sc-418080-ACT-2 from Santa Cruz Biotechnology
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WDR12 Lentiviral Activation Particles (h) - sc-418080-LAC from Santa Cruz Biotechnology
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WDR12 Lentiviral Activation Particles (h2) - sc-418080-LAC-2 from Santa Cruz Biotechnology
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WDR12 siRNA (h) - sc-94873 from Santa Cruz Biotechnology
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WDR12 shRNA Plasmid (h) - sc-94873-SH from Santa Cruz Biotechnology
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WDR12 shRNA (h) Lentiviral Particles - sc-94873-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU025691 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22805 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22805 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01511 from Sigma-Aldrich
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WDR12 siRNA (Human) - CRJ0897 from Cohesion Biosciences
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WDR12 - MBS8219194 from MyBioSource
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shRNA set against Human WDR12 (NM_018256.3) - SHH445908 from Creative biogene
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WDR12 shRNA Plasmid (Human) - CHJ0897 from Cohesion Biosciences
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WDR12 miRNA 3'UTR clone - MiUTR3H-16557 from Creative biogene
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