Gene Symbol |
RGN
|
Entrez Gene |
100008619
|
Alt Symbol |
GNL
|
Species |
Rabbit
|
Gene Type |
protein-coding
|
Description |
regucalcin
|
Other Description |
RC|SMP-30|gluconolactonase|regucalcin (senescence marker protein-30)|senescence marker protein 30
|
Swissprots |
Q9TTJ6
|
Accessions |
Q9TTJ6 AB035445 BAA88079 XM_008272336 XP_008270558 NM_001082003 NP_001075472
|
Function |
Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Catalyzes a key step in ascorbic acid (vitamin C) biosynthesis. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}.
|
Top Pathways |
Pentose phosphate pathway, Ascorbate and aldarate metabolism, Degradation of aromatic compounds, Carbon metabolism
|