Gene Symbol | Glud1 |
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Entrez Gene | 14661 |
Alt Symbol | AI118167, Gdh-X, Glud, Gludl |
Species | Mouse |
Gene Type | protein-coding |
Description | glutamate dehydrogenase 1 |
Other Description | GDH 1|glutamate dehydrogenase 1, mitochondrial |
Swissprots | Q8C273 P26443 |
Accessions | EDL24875 P26443 AK075971 AK089152 BAC40767 AK150637 AK161876 BAE36618 AK181205 AK207576 AK209048 AK213533 AK213994 AK217090 AK219236 AK219431 BC052724 AAH52724 BC057347 AAH57347 EF437367 X57024 CAA40341 NM_008133 NP_032159 |
Function | Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. {ECO:0000269|PubMed:23663782}. |
Subcellular Location | Mitochondrion matrix. |
Top Pathways | Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, D-Glutamine and D-glutamate metabolism |
GLUD1 CRISPR/Cas9 KO Plasmid (m) - sc-420587 from Santa Cruz Biotechnology
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GLUD1 HDR Plasmid (m) - sc-420587-HDR from Santa Cruz Biotechnology
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GLUD1 Double Nickase Plasmid (m) - sc-420587-NIC from Santa Cruz Biotechnology
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GLUD1 Double Nickase Plasmid (m2) - sc-420587-NIC-2 from Santa Cruz Biotechnology
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GLUD1 CRISPR Activation Plasmid (m) - sc-420587-ACT from Santa Cruz Biotechnology
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GLUD1 CRISPR Activation Plasmid (m2) - sc-420587-ACT-2 from Santa Cruz Biotechnology
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GLUD1 Lentiviral Activation Particles (m) - sc-420587-LAC from Santa Cruz Biotechnology
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GLUD1 Lentiviral Activation Particles (m2) - sc-420587-LAC-2 from Santa Cruz Biotechnology
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GLUD1 siRNA (m) - sc-145446 from Santa Cruz Biotechnology
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GLUD1 shRNA Plasmid (m) - sc-145446-SH from Santa Cruz Biotechnology
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GLUD1 shRNA (m) Lentiviral Particles - sc-145446-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU166611 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN31972 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND31972 from Sigma-Aldrich
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GLUD1 siRNA (Mouse) - CRM1590 from Cohesion Biosciences
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GLUD1 - MBS8216966 from MyBioSource
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shRNA set against Mouse GLUD1 (NM_008133.4) - SHH302206 from Creative biogene
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Mouse GLUD1 siRNA - orb281066 from Biorbyt
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GLUD1 shRNA Plasmid (Mouse) - CHM1590 from Cohesion Biosciences
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