| Gene Symbol | Glud1 |
|---|---|
| Entrez Gene | 14661 |
| Alt Symbol | AI118167, Gdh-X, Glud, Gludl |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | glutamate dehydrogenase 1 |
| Other Description | GDH 1|glutamate dehydrogenase 1, mitochondrial |
| Swissprots | Q8C273 P26443 |
| Accessions | EDL24875 P26443 AK075971 AK089152 BAC40767 AK150637 AK161876 BAE36618 AK181205 AK207576 AK209048 AK213533 AK213994 AK217090 AK219236 AK219431 BC052724 AAH52724 BC057347 AAH57347 EF437367 X57024 CAA40341 NM_008133 NP_032159 |
| Function | Mitochondrial glutamate dehydrogenase that converts L- glutamate into alpha-ketoglutarate. Plays a key role in glutamine anaplerosis by producing alpha-ketoglutarate, an important intermediate in the tricarboxylic acid cycle. May be involved in learning and memory reactions by increasing the turnover of the excitatory neurotransmitter glutamate. {ECO:0000269|PubMed:23663782}. |
| Subcellular Location | Mitochondrion matrix. |
| Top Pathways | Nitrogen metabolism, Proximal tubule bicarbonate reclamation, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, D-Glutamine and D-glutamate metabolism |