Gene Symbol | PPT1 |
---|---|
Entrez Gene | 5538 |
Alt Symbol | CLN1, INCL, PPT |
Species | Human |
Gene Type | protein-coding |
Description | palmitoyl-protein thioesterase 1 |
Other Description | ceroid-palmitoyl-palmitoyl-protein thioesterase 1|palmitoyl-protein hydrolase 1 |
Swissprots | Q6FGQ4 B4DY24 P50897 |
Accessions | AAA85337 AAB72224 CBX51404 EAX07237 EAX07238 P50897 AK075496 AK301682 BAG63155 AK302232 BAG63586 AK310799 AK312287 BAG35214 BC008426 AAH08426 BX441569 CR542053 CAG46850 DA504318 HQ447414 ADQ31900 U44772 AAB06236 XM_005271008 XP_005271065 NM_000310 NP_000301 NM_001142604 NP_001136076 |
Function | Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. |
Subcellular Location | Lysosome. |
Top Pathways | Lysosome, Fatty acid elongation, Fatty acid metabolism |