GPN1

Gene Symbol GPN1
Entrez Gene 11321
Alt Symbol ATPBD1A, MBDIN, NTPBP, RPAP4, XAB1
Species Human
Gene Type protein-coding
Description GPN-loop GTPase 1
Other Description ATP(GTP)-binding protein|MBD2-interacting protein|RNA polymerase II associated protein 4|RNAPII-associated protein 4|XPA binding protein 1, GTPase
Swissprots B4DXU4 B4DQJ5 O76004 B4DQM4 B5MBZ5 Q9HCN4
Accessions AAX93201 EAX00557 EAX00558 Q9HCN4 AB044661 BAB17612 AJ010842 CAA09376 AK298827 BAG60957 AK298866 BAG60986 AK302131 BAG63506 AK310340 AK311423 AK312992 BAG35829 AK316404 BAH14775 BC007451 AAH07451 DQ893280 ABM84206 DQ896611 ABM87610 NM_001145047 NP_001138519 NM_001145048 NP_001138520 NM_001145049 NP_001138521 NM_007266 NP_009197 NR_026735
Function Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119). {ECO:0000269|PubMed:17643375, ECO:0000269|PubMed:20855544, ECO:0000269|PubMed:21768307, ECO:0000305|PubMed:11058119}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:11058119, ECO:0000269|PubMed:20855544}. Nucleus {ECO:0000269|PubMed:20855544}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000269|PubMed:20855544}.
Tissue Specificity Expressed ubiquitously.

XAB1 (C-14) - sc-169817 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

XAB1 (D-15) - sc-169818 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

XAB1 (H-248) - sc-135356 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
XAB1 (H-248): sc-135356. Western blot analysis of XAB1 expression in Ramos (A), HL-60 (B) and IMR-32 (C) whole cell lysates.

Anti-XAB1 antibody - ab56974 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
XAB1 antibody (ab56974) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human stomach.

Anti-XAB1 antibody - ab50265 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-XAB1 antibody - ab88445 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-XAB1 antibody (ab88445) at 1 µg/ml + Human liver lysate at 50 µg

Anti-XAB1 antibody - ab129794 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-XAB1 antibody (ab129794) at 1/100 dilution + 293 cell lysate at 35 µg

Anti-GPN1 / XAB1 Antibody (clone 3E1) IHC-plus™ - LS-B4516 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3E1
Anti-GPN1 / XAB1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4516 concentration 5 ug/ml.

Anti-GPN1 / XAB1 Antibody (aa324-352, AP) - LS-C222650 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody (aa324-352, PE) - LS-C222656 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody (aa324-352, Azide-free, HRP) - LS-C222655 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody (aa324-352, FITC) - LS-C222654 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody (aa324-352, APC) - LS-C222652 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody (aa324-352, Biotin) - LS-C222653 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody - LS-C311187 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody (aa9-119, Azide-free) - LS-C329117 from LifeSpan Bioscience

Prices $485.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-GPN1 / XAB1 Antibody (aa324-352) - LS-C329593 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GPN1 / XAB1 Antibody (aa325-352) - LS-C166616 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GPN1 Antibody western blot of 293 cell line lysates (35 ug/lane). The GPN1 antibody detected the GPN1 protein (arrow).

XAB1 Antibody (3E1) - H00011321-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3E1
Western Blot: XAB1 Antibody (3E1) [H00011321-M01] - XAB1 monoclonal antibody (M01), clone 3E1 Analysis of XAB1 expression in HL-60.

XAB1 Antibody - NBP1-90072 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

XAB1 Antibody - NBP2-38332 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: XAB1 Antibody [NBP2-38332] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG

XAB1 Antibody - H00011321-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: XAB1 Antibody [H00011321-B01P] - Analysis of XAB1 expression in human liver.

XAB1 Antibody - NBP2-37686 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: XAB1 Antibody [NBP2-37686] - Whole cell lysate (50 ug) from HeLa, 293T, and Jurkat cells prepared using NETN lysis buffer. Affinity purified rabbit anti-GPN1 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

XAB1 Antibody - H00011321-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-XAB1 antibody produced in mouse - SAB1407135 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-XAB1: <B>Cat. No. SAB1407135</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~41.7 kDa using HeLa lysate.
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