| Gene Symbol | CELE_H42K12.1 |
|---|---|
| Entrez Gene | 180475 |
| Alt Symbol | - |
| Species | C. elegans |
| Gene Type | protein-coding |
| Description | PDK-1 |
| Other Description | - |
| Swissprots | Q9Y1J3 Q9UA36 |
| Accessions | CCD67851 CCD67852 Q9Y1J3 AF130406 AAD42307 AF130407 AAD42308 NM_001029571 NP_001024742 NM_001029572 NP_001024743 |
| Function | Involved in the daf-2/insulin receptor-like transduction pathway, which controls longevity and prevents developmental arrest at the dauer stage. Phosphorylates and activates sgk-1, akt-1 and akt-2. {ECO:0000269|PubMed:10364160, ECO:0000269|PubMed:15068796}. |
| Subcellular Location | Cytoplasm {ECO:0000250}. |
| Top Pathways | mTOR signaling pathway |
PDK-1, Monoclonal Antibody - MBS606108 from MyBioSource
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