Gene Symbol |
WNT3A
|
Entrez Gene |
89780
|
Alt Symbol |
-
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
wingless-type MMTV integration site family, member 3A
|
Other Description |
protein Wnt-3a
|
Swissprots |
Q3SY79 P56704 Q3SY80 Q969P2
|
Accessions |
CAI38643 CDH92868 EAW69829 P56704 AB060284 BAB61052 AK056278 BAB71136 BC103921 AAI03922 BC103922 AAI03923 BC103923 AAI03924 CA437424 DA742143 XM_011544319 XP_011542621 XM_011544320 XP_011542622 NM_033131 NP_149122
|
Function |
Ligand for members of the frizzled family of seven transmembrane receptors. Wnt-3 and Wnt-3a play distinct roles in cell-cell signaling during morphogenesis of the developing neural tube.
|
Subcellular Location |
Secreted, extracellular space, extracellular matrix.
|
Tissue Specificity |
Moderately expressed in placenta and at low levels in adult lung, spleen, and prostate.
|
Top Pathways |
HTLV-I infection, Proteoglycans in cancer, Signaling pathways regulating pluripotency of stem cells, MicroRNAs in cancer, Hippo signaling pathway
|