Gene Symbol | SARS2 |
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Entrez Gene | 54938 |
Alt Symbol | SARS, SARSM, SERS, SYS, SerRS, SerRSmt, mtSerRS |
Species | Human |
Gene Type | protein-coding |
Description | seryl-tRNA synthetase 2, mitochondrial |
Other Description | mitochondrial seryl-tRNA synthetase|serine tRNA ligase 2, mitochondrial|serine--tRNA ligase, mitochondrial|serine-tRNA ligase, mitochondrial|seryl-tRNA synthetase, mitochondrial|seryl-tRNA(Ser/Sec) synthetase |
Swissprots | Q9BVP3 Q9NP81 B4DE10 A6NHW7 |
Accessions | EAW56844 EAW56845 EAW56846 EAW56847 EAW56848 Q9NP81 AB029948 BAA99557 AK000457 BAA91176 AK098522 AK293414 BAG56921 AK296152 BAG58891 AK296170 BAG58908 BC001020 AAH01020 BC042912 AAH42912 CA415983 NM_001145901 NP_001139373 NM_017827 NP_060297 |
Function | Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity). {ECO:0000250}. |
Subcellular Location | Mitochondrion matrix {ECO:0000250}. |
Top Pathways | Aminoacyl-tRNA biosynthesis |
SerRSmt CRISPR/Cas9 KO Plasmid (h) - sc-409979 from Santa Cruz Biotechnology
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SerRSmt HDR Plasmid (h) - sc-409979-HDR from Santa Cruz Biotechnology
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SerRSmt Double Nickase Plasmid (h) - sc-409979-NIC from Santa Cruz Biotechnology
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SerRSmt Double Nickase Plasmid (h2) - sc-409979-NIC-2 from Santa Cruz Biotechnology
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SerRSmt CRISPR Activation Plasmid (h) - sc-409979-ACT from Santa Cruz Biotechnology
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SerRSmt CRISPR Activation Plasmid (h2) - sc-409979-ACT-2 from Santa Cruz Biotechnology
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SerRSmt Lentiviral Activation Particles (h) - sc-409979-LAC from Santa Cruz Biotechnology
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SerRSmt Lentiviral Activation Particles (h2) - sc-409979-LAC-2 from Santa Cruz Biotechnology
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SerRSmt siRNA (h) - sc-97305 from Santa Cruz Biotechnology
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SerRSmt shRNA Plasmid (h) - sc-97305-SH from Santa Cruz Biotechnology
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SerRSmt shRNA (h) Lentiviral Particles - sc-97305-V from Santa Cruz Biotechnology
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Seryl tRNA synthetase RNAi - H00006301-R01V from Novus Biologicals
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Seryl tRNA synthetase RNAi - H00006301-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN18854 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18854 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02315 from Sigma-Aldrich
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SARS2 siRNA (Human) - CRJ0341 from Cohesion Biosciences
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SARS2 - MBS8223746 from MyBioSource
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shRNA set against Human SARS2 (NM_017827.3) - SHH401928 from Creative biogene
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Human SARS2 siRNA - orb270842 from Biorbyt
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SARS2 shRNA Plasmid (Human) - CHJ0341 from Cohesion Biosciences
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SARS2 miRNA 3'UTR clone - MiUTR3H-12607 from Creative biogene
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SARS2 miRNA 3'UTR clone - MiUTR3H-12608 from Creative biogene
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