Gene Symbol | ST14 |
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Entrez Gene | 6768 |
Alt Symbol | ARCI11, HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14 |
Species | Human |
Gene Type | protein-coding |
Description | suppression of tumorigenicity 14 (colon carcinoma) |
Other Description | membrane-type serine protease 1|prostamin|serine protease 14|serine protease TADG-15|suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)|suppressor of tumorigenicity 14 protein|tumor associated differentially expressed gene 15 protein|tumor-associated differentially-expressed gene 15 protein |
Swissprots | Q9HCA3 Q9BS01 Q9Y5Y6 Q9HB36 Q9H3S0 |
Accessions | AAG13949 EAW67776 Q9Y5Y6 AB030036 BAB20376 AF057145 AAG15395 AF118224 AAD42765 AF133086 AAF00109 AK302454 BAG63749 AK314173 BAG36856 BC005826 AAH05826 BC018146 AAH18146 BC030532 AAH30532 BM791311 BQ059215 DQ891626 ABM82552 DQ894442 ABM85368 NM_021978 NP_068813 |
Function | Degrades extracellular matrix. Proposed to play a role in breast cancer invasion and metastasis. Exhibits trypsin-like activity as defined by cleavage of synthetic substrates with Arg or Lys as the P1 site. Involved in the terminal differentiation of keratinocytes through prostasin (PRSS8) activation and filaggrin (FLG) processing. {ECO:0000269|PubMed:18843291}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}. |
Top Pathways | MicroRNAs in cancer |
Human ST14 full length protein - ab114597 from Abcam
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Human ST14 protein fragment - ab114598 from Abcam
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ST14 peptide - ab41262 from Abcam
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ST14 peptide - ab41263 from Abcam
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ST14 peptide - ab41264 from Abcam
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ST14 peptide - ab41265 from Abcam
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ST14 / Matriptase Antibody Blocking Peptide - LS-E17390 from LifeSpan Bioscience
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Matriptase/ST14 Partial Recombinant Protein - H00006768-Q01 from Novus Biologicals
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Recombinant Human Matriptase/ST14 Catalytic Domain, CF - 3946-SE-010 from R&D Systems
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ST14 Blocking Peptide - 33R-8520 from Fitzgerald
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ST14 Blocking Peptide - 33R-7953 from Fitzgerald
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Human ST14 Protein - abx069206 from Abbexa
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ST14 / Matriptase - H00006768-P01-10 from Acris Antibodies
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ST14 / Matriptase - H00006768-P01-25 from Acris Antibodies
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ST14 / Matriptase - H00006768-Q01-10 from Acris Antibodies
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ST14 / Matriptase - H00006768-Q01-25 from Acris Antibodies
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Suppression Of Tumorigenicity 14 (ST14), Human - 20-9575 from ARP American Research Products
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ST14 fusion protein - ag5924 from Proteintech Group
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ST14 fusion protein - ag5928 from Proteintech Group
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Recombinant Human ST14 - ST14-30315TH from Creative Biomart
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Recombinant Human ST14 - ST14-31173TH from Creative Biomart
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Recombinant Human ST14, His-tagged - ST14-256H from Creative Biomart
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Recombinant Human ST14, His-tagged - ST14-2977H from Creative Biomart
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Recombinant Human ST14, Met & His-tagged - ST14-742H from Creative Biomart
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Recombinant Suppression Of Tumorigenicity 14 (ST14) - RPP657Hu01 from Uscn Life Science Inc.
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